Figure 1.

(A) Cytopathic effect of SARS-CoV-2 infection on African Green Monkey kidney cells (Vero-E6); (A1). Infected Vero cells on day 4 post infection with magnification 10×; (A2) infected cells at 40× magnification. A3 and A4 are Vero-E6 cells infected with the inactivated vaccine at magnification 10× and 40×, respectively. (B) RNA copy numbers of cultivated virus with and without TPCK-treated trypsin. The significant differences are indicated (* = p < 0.05). (C) Western blot protein profiles of cultivated viruses before and after concentration. Immunogenic peptides S and NP were characterized at about 270 and 55 kilodalton (kDa), respectively. (D) Electron microscope image of cultivated SARS-CoV-2 virus.