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D-α-tocopheryl-polyethylene-glycol-succinate (TPGS) concentration-dependent solubility of all-trans-retinoic acid (ATRA). Total solubility of ATRA versus TPGS concentration measured by equilibrium method after 48 h at 37 °C in water (a). Linear regression obtained considering the values above TPGS critical micellar concentration (CMC) (b).
