| [18F]FPEB | 3-[18F]fluoro-5-(2-pyridinylethynyl)benzonitrile |
| ADI-R | Autism Diagnostic Interview-Revised [50] |
| ADOS | Autism Diagnostic Observation Schedule [51] |
| ANOVA | analysis of variance |
| ASD | autism spectrum disorder |
| BMI | basal metabolic index |
| BPND | non-displaceable binding potential |
| CEA | Commissariat à l’Énergie Atomique et aux Énergies Alternatives |
| CDC | Centers for Disease Control and Prevention |
| CN | caudate nucleus |
| CNAMI | CNS Neuropsychopharmacology and Multimodal Imaging |
| CNMT | Certified Nuclear Medicine Technologist |
| CNRS | Centre National de la Recherche Scientifique |
| CNS | central nervous system |
| DSM-5 | Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition [1] |
| DTI | diffusion tensor imaging |
| EEG | electroencephalography |
| ERK | extracellular signal-regulated kinase |
| ERP | event-related brain potential |
| FORWARD | Fragile X Online Registry With Accessible Research Database of the National Fragile X Foundation (NFXF) |
| FMR1 | fragile X mental retardation 1 gene |
| fmr1 | fmr1 gene in knockout mouse model of fragile X syndrome |
| FMRP | Fragile X Mental Retardation Protein |
| FXS | fragile X syndrome |
| FXS-M | fragile X syndrome allele size mosaicism |
| GABA | gamma amino butyric acid |
| HRRT | high resolution research tomograph [53] |
| HSD | Honest Standard Differences [31] |
| IASD | idiopathic autism spectrum disorder |
| ID | intellectual disability |
| IND | Institute for Neurodegenerative Disorders |
| IJMS | International Journal of Molecular Sciences |
| JHU | Johns Hopkins University |
| KO | knockout |
| LTD | long-term depression |
| MDPI | Multidisciplinary Digital Publishing Institute |
| MPAK | mitogen-activated protein kinase (MAPK) |
| MBq | megabecquerel |
| mCi | millicurie |
| mGluR1/5 | metabotropic glutamate receptors subtypes 1 and 5 |
| mGluR5 | metabotropic glutamate receptor subtype 5 |
| mGluR-LTD | metabotropic glutamate receptor dependent longterm depression |
| MIRCen | Molecular Imaging Research Center |
| MR | magnetic resonance |
| MRS | magnetic resonance spectroscopy |
| mTOR | mammalian target of rapamycin |
| mTp | medial temporal cortex |
| NAM | negative allosteric modulator |
| NFXF | National Fragile X Foundation |
| NMTCB | Nuclear Medicine Technology Certification Board |
| Oc | occipital cortex |
| Pa | parietal cortex |
| pCg | posterior cingulate cortex |
| PCR | polymerase chain reaction |
| PET | positron emission tomography |
| PET/MRI | positron emission tomography/magnetic resonance imaging |
| Pu | putamen |
| ROI | region of interest |
| rs-fMRI | resting state functional magnetic resonance imaging |
| RTGA | reference tissue graphical analysis |
| SPM | Statistical Parametric Mapping |
| TD | typical development |
| Th | thalamus |
| Tp | temporal cortex |
| (period) | missing data |