DC |
dendritic cell |
cDC |
conventional DC |
pDC |
plasmacytoid dendritic DC |
moDC |
dendritic cell derived from monocytes |
Mφs |
macrophages |
PAMP |
pathogen associated molecular pattern |
PRRs |
pattern recognition receptors |
TLR |
toll-like receptor |
RLR |
retinoic acid-inducible gene I-like receptor |
NLR |
NOD-like receptor |
NFIL3 |
IL-3-regulated protein |
LAG-3 |
lymphocyte activation marker 3 |
IBD |
inflammatory bowel disease |
CD |
Crohn’s disease |
UC |
ulcerative colitis |
GM-CSF |
granulocyte/Mφ colony stimulating factor |
SCFA |
short chain fatty acid |
TGF |
transforming growth factor |
PD-1 |
programmed death receptor 1 |
PD-L1 |
programmed death receptor 1 ligand |
IECs |
intestinal epithelium cells |
CARD9 |
caspase recruitment domain 9 |
Th |
T helper cells |
PPARγ |
peroxisome proliferator-activated receptor γ |
RA |
retinoic acid |
DSS |
dextran sulphate sodium |
WASP |
Wiskott–Aldrich syndrome protein |
Dab2 |
disabled homolog 2 |
inf-DCs |
inflammatory DCs |
ROS |
reactive oxygen species |
IDO |
indoleamine 2,3-dioxygenase |
Trp |
tryptophan |
Kyn |
kynurenine |
NF-κB |
nuclear factor kappa B subunit |
TGF |
transforming growth factor |
TNF, |
tumor necrosis factor |
VEGF |
vascular endothelial growth factor |
GF |
germ free |