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. 2021 Mar 6;10(3):583. doi: 10.3390/cells10030583
DC dendritic cell
cDC conventional DC
pDC plasmacytoid dendritic DC
moDC dendritic cell derived from monocytes
Mφs macrophages
PAMP pathogen associated molecular pattern
PRRs pattern recognition receptors
TLR toll-like receptor
RLR retinoic acid-inducible gene I-like receptor
NLR NOD-like receptor
NFIL3 IL-3-regulated protein
LAG-3 lymphocyte activation marker 3
IBD inflammatory bowel disease
CD Crohn’s disease
UC ulcerative colitis
GM-CSF granulocyte/Mφ colony stimulating factor
SCFA short chain fatty acid
TGF transforming growth factor
PD-1 programmed death receptor 1
PD-L1 programmed death receptor 1 ligand
IECs intestinal epithelium cells
CARD9 caspase recruitment domain 9
Th T helper cells
PPARγ peroxisome proliferator-activated receptor γ
RA retinoic acid
DSS dextran sulphate sodium
WASP Wiskott–Aldrich syndrome protein
Dab2 disabled homolog 2
inf-DCs inflammatory DCs
ROS reactive oxygen species
IDO indoleamine 2,3-dioxygenase
Trp tryptophan
Kyn kynurenine
NF-κB nuclear factor kappa B subunit
TGF transforming growth factor
TNF, tumor necrosis factor
VEGF vascular endothelial growth factor
GF germ free