Table 3.
Cancer-related miRNAs present in the blood with a high expression falling in the upper quartile of the distribution of intensity expression. The intensity of the miRNA expression was reported in fluorescence units as detected by microarray analysis (middle column). The miRNAs found in our study were compared with the bibliography to evaluate if their dysregulation in the blood could be considered as potential markers for lung cancer (right column).
| Tumoral miRNAs in Blood | Average Signal in Blood Plasma Microarray (Fluorescence Units) |
Reference in Literature |
|---|---|---|
| hsa-let-7b-5p | 1556.03 | [16,17] |
| hsa-let-7e-5p | 2570.68 | [15] |
| hsa-let-7g-5p | 1591.89 | ND |
| hsa-miR-103a-3p | 1966.77 | ND |
| hsa-miR-107 | 2307.96 | ND |
| hsa-miR-1247-5p | 1619.35 | ND |
| hsa-miR-143-3p | 1517.48 | ND |
| hsa-miR-147b | 2867.22 | ND |
| hsa-miR-150-5p | 1728.39 | [15] |
| hsa-miR-151a-5p | 2375.45 | ND |
| hsa-miR-151b | 2375.45 | ND |
| hsa-miR-181a-2-3p | 1714.68 | ND |
| hsa-miR-183-3p | 4515.51 | ND |
| hsa-miR-184 | 3097.26 | ND |
| hsa-miR-185-5p | 2809.76 | ND |
| hsa-miR-193a-5p | 1482.98 | ND |
| hsa-miR-22-5p | 1889.39 | [15,17] |
| hsa-miR-224-3p | 1805.07 | ND |
| hsa-miR-23a-5p | 2880.99 | ND |
| hsa-miR-26a-5p | 1497.29 | [17] |
| hsa-miR-2861 | 3086.05 | ND |
| hsa-miR-29b-2-5p | 1481.13 | ND |
| hsa-miR-30b-5p | 2117.35 | [16] |
| hsa-miR-30c-2-3p | 2919.97 | ND |
| hsa-miR-30c-5p | 3299.46 | [17,18] |
| hsa-miR-3149 | 2367.91 | ND |
| hsa-miR-361-3p | 1454.65 | ND |
| hsa-miR-371b-5p | 12,583.51 | ND |
| hsa-miR-424-5p | 1660.83 | ND |
| hsa-miR-4252 | 1558.12 | ND |
| hsa-miR-4290 | 1875.54 | ND |
| hsa-miR-4306 | 7145.12 | ND |
| hsa-miR-4324 | 1530.87 | ND |
| hsa-miR-4440 | 1537.86 | ND |
| hsa-miR-4443 | 3859.37 | ND |
| hsa-miR-4481 | 1605.44 | ND |
| hsa-miR-450a-5p | 4646.58 | ND |
| hsa-miR-4516 | 11,603.31 | ND |
| hsa-miR-452-5p | 1629.61 | ND |
| hsa-miR-4532 | 13,231.17 | ND |
| hsa-miR-4634 | 1884.47 | ND |
| hsa-miR-483-3p | 3177.46 | ND |
| hsa-miR-486-3p | 2337.52 | [14,18] |
| hsa-miR-490-3p | 1882.31 | ND |
| hsa-miR-505-5p | 3775.67 | ND |
| hsa-miR-516b-5p | 5121.31 | ND |
| hsa-miR-548aa | 3480.4 | ND |
| hsa-miR-548q | 1453.76 | ND |
| hsa-miR-642b-5p | 2070.84 | ND |
| hsa-miR-664b-3p | 1539.91 | ND |
| hsa-miR-744-5p | 3112.18 | ND |
| hsa-miR-99a-3p | 1503.5 | ND |
| hsa-miR-99b-5p | 1575.63 | ND |
ND, Not Detected.