Table 2.

Study characteristics.

Authors and Publication Year	Study Characteristic					Intervention
	Sample	Age	Country	Duration	Design
A. Hernaez et al., 2019 [13]	196 individuals from the PREDIMED study	55–80	Spain	1 year	Randomized controlled trial	Traditional MD—VOO Traditional MD–nuts Traditional MD—fish Traditional MD—legumes Traditional MD—whole grains
A. Hernaez et al., 2017 [14]	296 individuals from the PREDIMED study	55–80	Spain	1 year	Randomized controlled trial	Traditional MD—nuts Traditional MD—VOO Low-fat diet
A. Hernaez et al., 2014 [15]	47 individuals from the EUROLIVE study	20–60	Germany Spain Finland	3 weeks	Randomized controlled trial	HPCOO LPCOO
N. Tanaka et al., 2014 [20]	28 dyslipidemic individuals	50–85	Japan	4 weeks	Randomized trial	Low-fat diet enriched with EPA
R. Sola et al., 2011 [21]	772 individuals from the PREDIMED study	55–80	Spain	3 months	Randomized controlled trial	Traditional MD—VOO Traditional MD—nuts Low-fat diet
J. McEneny et al., 2013 [16]	54 overweight individuals	45–55	UK	12 weeks	Randomized controlled trial	Lycopene rich diet Lycopene supplemented diet
C. Zhu et al., 2019 [17]	10 healthy individuals	18–25	California	4 days	Randomized crossover trial	Fast food diet MD
O. Helal et al., 2013 [18]	26 healthy individuals	18–75	Canada	12 weeks	Randomized trial	Extra VOO
M. Farras et al., 2015 [22] S. Fernandez-Castillejo et al., 2017 [23] M. Farras et al., 2018 [24] A. Pedret et al., 2015 [25]	33 individuals of the VOHF study	35–80	Spain	3 weeks	Randomized controlled trial	VOO FVOO FVOOT
R. Sola et al., 1997 [19]	22 healthy individuals	45–55		8 weeks	Randomized crossover trial	MD rich in oleic MD rich in linoleic

MD, Mediterranean diet; VOO, virgin olive oil; HPCOO, high-polyphenol content olive oil; LPCOO, low-polyphenol content olive oil; EPA, eicosapentaenoic acid; FVOO, functional virgin olive oil; FVOOT, functional olive oil with thyme; UK, United Kingdom.