Table 1.
Summary of feature numbers in each omics dataset as a function o.f cutoff value. Total numbers of features/molecules identified in all samples (without exception) obtained from high-risk T1D and healthy subjects (n = 4 each), and numbers of remaining features after data selection using different fold-change cutoff values.
| Fold-Change 1 | Proteomics | Transcriptomics | Metabolomics | Lipidomics | Total |
|---|---|---|---|---|---|
| All | 2292 | 328 | 75 | 41 | 2736 |
| 1.1 | 260 | 95 | 75 | 8 | 438 |
| 1.2 | 151 | 87 | 75 | 5 | 318 |
| 1.3 | 107 | 80 | 75 | 3 | 265 |
| 2.0 | 18 | 47 | 30 | 0 | 95 |
| 3.0 | 7 | 29 | 0 | 0 | 36 |
1 Used as cutoff value for feature selection in all the datasets and input into the integrative analysis in IPA software (QIAGEN Bioinformatics).