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Potential synergy between vitamin K and vitamin D action in bone. Abbreviations: IL-6, interleukin 6; TNF-α, tumor necrosis factor α; CRP, C-reactive protein; 1,24,25D, 1,24,25-trihydroxyvitamin D; 1,25-dihydroxyvitamin D; CYP-24, 25-hydroxyvitamin D-24α-hydroxylase; VDR, vitamin D receptor; SXR, steroid and xenobiotic receptor; BGLAP, bone-Gla-protein; ucOC, uncarboxylated osteocalcin; cOC, carboxylated osteocalcin.
