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Meis1/2 deletion results in expansion of the CMZ. (A−P′) Immunostaining with Cdo, Msx1, Zic1, FoxP2, Brn3a, phosphorylated Smad1/5, Lef1, Six3, and Sox2 antibodies in frontal sections of control and Meis1/2 cKO embryos at E14.5. Magnified views indicated by the white boxed areas of top images are shown below. The dorsal-ventral axis is indicated by an arrow. (Scale bars, 50 μm.)
