Table 3.
Selected examples of hydrogel-based commercial dosage forms for oral delivery.
| Commercial Product | Polymers | Active Constituents | Dosage Form | Application | Manufacturer |
|---|---|---|---|---|---|
| Buccastem® M | Povidone K30, xanthan gum, locust bean gum | Prochlorperazine maleate | Tablet | Nausea and vomiting in migraine | Alliance |
| Biotene | Carbomer and hydroxyethyl cellulose | Nil | Gel | Oral moisturizing agent in dry mouth | GlaxoSmithKline |
| Gengigel® | Hyaluronan | Nil | Gel | Mouth and gum care-oral ulcers | Oral Science |
| Hydrogel 15% | Carbomer in ozonized sunflower oil | Ozone | Gel | Oral health | Honest 03 |
| Lubrajel™ BA | Glyceryl acrylate and glyceryl polyacrylate | Nil | Gel | Oral moisturizing agent | Prospector |
| Nicorette® | Hydroxypropyl methylcellulose | Nicotine | Chewing gum | Smoking cessation | GlaxoSmithKline |
| Nicotinell® | Xanthan gum and gelatin | Nicotine | Chewing gum | Smoking cessation | GlaxoSmithKline |
| Zilactin-B Gel® | Hydroxypropyl cellulose | Benzocaine | Gel | Local anesthetic in minor oral problems | Blairex laboratories Inc. |
| ZuplenzTM | Polyethylene glycol 1000, polyvinyl alcohol and rice starch | Ondansetron | Soluble oral film | Chemotherapy, radiation, surgery-induced nausea and vomiting | Aquestive Therapeutics |