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. 2021 Mar 8;13(3):357. doi: 10.3390/pharmaceutics13030357

Table 4.

Selected commercial examples of hydrogel-based ocular drug delivery systems and soft contact lens materials.

Product Name Principal Components Indications Manufacturer
Biofinity® Silicone hydrogel Continuous wear up to 7 days. Corrects near sightedness and farsightedness Cooper vision
Air optix® night and day®aqua Lotrafilcon-A (fluoro-silicone hydrogel) Continuous wear up to 7 days. Corrects near sightedness and farsightedness Alcon
Retisert® Fluocinolone acetonide, silicone elastomer and polyvinyl alcohol membrane Deliver long term control of inflammation Bausch and Lomb
Lacrisert® Hydroxypropyl cellulose Moderate to severe dry eyes Bausch and Lomb
Systane® Propylene glycol For use as a lubricant to prevent further irritation or to relieve dryness of the eye Alcon
Restasis® Cyclosporine, carbomer copolymer Type A Indicated to increase tear production Allergan
Proclear (Omafilcon B) 2-hydroxy-ethylmethacrylate and 2-methacryloxyethyl phosphorylcholine cross-linked with ethylene glycol dimethacrylate Indicated for daily wear for the correction of visual acuity Cooper vision
Clintas Hydrate® Carbomer Lubricating eye gel for occasional dry eye discomfort Altacor
Dailies® AquaComfort Nelfilcon A polymer (polyvinyl alcohol partially acetalized with N-formylmethyl acrylamide) Optical correction of refractive ametropia Ciba vision
Systane® gel drops Polyethylene glycol 400, propylene glycol For the temporary relief of burning and irritation due to dryness of the eye Alcon
Hylo® gel Sodium hyaluronate, citrate buffer, sorbitol Long lasting dry eye relief Candorvision
Iluvien® Fluocinolone acetonide, polyvinyl alcohol, and silicone
adhesives
Treatment of diabetic macular edema Alimera Sciences
Yutiq™ Fluocinolone acetonide, polyvinyl alcohol Treatment of chronic non-infectious uveitis affecting the posterior segment of the eye EyePoint Pharmaceuticals Inc.
Ozurdex® Dexamethasone, poly (d,l-lactide-co-glycolide) Macular edema, non-infectious uveitis Allergan