Table 2.

Kinetics parameters and goodness of the fits of RES release from loaded MSNs. k_F: first-order rate constant independent of drug concentration; k_KP: constant incorporating characteristics of the system; NFW: Noyes–Whitney and Fick’s law equation; K–P: Korsmeyer–Peppas model.

Model		MSN/RES30		MSN/RES40
		pH 5.2	pH 7.4	pH 5.2	pH 7.4
NWF	kF (min−1)	1.41 × 10−3	1.05 × 10−3	1.12 × 10−3	6.0 × 10−4
	R2	0.9500	0.9530	0.9703	0.9694
	χ2	0.166	0.262	0.173	0.335
K–P	kKP (min−n)	0.0247	0.0256	0.01877	0.01343
	n	0.4865	0.4513	0.5090	0.4972
	R2	0.9751	0.9712	0.9636	0.9666
	χ2	0.033	0.028	0.043	0.024
Weibull	α (min−β)	121.3	164.6	87.12	429.0
	β	0.7214	0.7318	0.6357	0.8072
	R2	0.9749	0.9690	0.9902	0.9708
	χ2	0.044	0.055	0.034	0.097