Table 5.
Pathway enrichment analysis of the hub genes.
| Table | Description | Count | p-Value | Gene Symbol |
|---|---|---|---|---|
| hsa05219 | Bladder cancer | 4 | 0.0002 | CXCL8, SRC, EGFR, VEGFA |
| hsa04068 | FoxO signaling pathway | 4 | 0.006 | IL6, CCNB1, PLK1, EGFR |
| hsa05206 | MicroRNAs in cancer | 5 | 0.008 | DNMT1, PTGS2, EGFR, EZH2, VEGFA |
| hsa04370 | VEGF signaling pathway | 3 | 0.013 | SRC, PTGS2, VEGFA |
| hsa05120 | Epithelial cell signaling in Helicobacter pylori infection | 3 | 0.016 | CXCL8, SRC, EGFR |
| hsa05200 | Pathways in cancer | 5 | 0.024 | IL6, CXCL8, PTGS2, EGFR, VEGFA |
| hsa04066 | HIF1 signaling pathway | 3 | 0.031 | IL6, EGFR, VEGFA |
| hsa04110 | Cell cycle | 3 | 0.049 | CCNB1, PCNA, PLK1 |
Enrichment analysis was done using DAVID and a set count >2 and p < 0.05 as the cut-off for significant enrichment. List of hub genes enriched in different pathways are presented.