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Summary of hiPSC-CM cell type responses to intermediate-risk compounds. A, Intermediate-risk compounds effects on spontaneous beat rate, Hz. B, Intermediate-risk compound effects on APD90 values. C, Intermediate-risk compound effects on the APD90 relative to vehicle control values. The ETPC is positioned on each plot in (C) to provide context for the drug concentration relative to documented therapeutic levels. All data expressed as mean±SEM.
