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. 2021 Mar 15;118(12):e2022403118. doi: 10.1073/pnas.2022403118

Fig. 6.

Fig. 6.

The effect of ARS-1620, BAY-293, and Kobe0065 on assemblies of KRas and SOScat. (A–E) Mass spectrum recorded after adding 10 µM ARS-1620 to preincubated mixtures of 1 µM SOScat with 3 µM (A) KRasG12C–GDP and (E) KRASG12C–GTP. Mass spectra are shown as described in Fig. 1. (B–F) Mass spectrum recorded after adding 2.5 µM Kobe0065 to preincubated mixtures of 1 µM SOScat with 3 µM (B) KRas–GTP and (F) KRASG13D–GTP (C–G) Mass spectrum recorded after adding 2.5 µM BAY-293 to preincubated mixtures of 1 µM SOScat with 3 µM (C) KRas–GTP and (G) KRASG13D–GTP. (D–H) Mass spectrum recorded after adding 2.5 µM BI-3406 to preincubated mixtures of 1 µM SOScat with 3 µM (D) KRas–GTP and (H) KRASG13D–GTP.