Table 3.
Type of Analysis | Outcome | k | MD | p-Value | 95% CI | I2 | Evidence of Publication Bias |
---|---|---|---|---|---|---|---|
Random-effect meta-analyses | |||||||
Pooled effect sizes | Diastolic BP | 6 | −2.029 | 0.016 | −3.676 to 0.383 | 0.000 | No (intercept = 1.060, t(4) = 0.979, p = 0.191) |
Pooled effect sizes | Systolic BP | 6 | −3.894 | 0.047 | −7.736 to 0.053 | 20.772 | No (intercept = −0.636, t(4) = 0.376, p = 0.362) |
Sensitivity analyses | |||||||
Excluding the studies with high risk of bias | Diastolic BP | 3 | −3.057 | 0.000 | −4.030 to −2.084 | 0.000 | No (intercept = −0.305, t(1) = 0.494, p = 0.353) |
Excluding the studies with high risk of bias | Systolic BP | 3 | −3.544 | 0.232 | −9.359 to 2.271 | 38.879 | No (intercept = −0.448, t(1) = 0.100, p = 0.468) |
Sensitivity analyses | |||||||
MBSR versus wait list | Diastolic BP | 2 | −0.944 | 0.565 | −4.159–2.271 | 0.000 | N/A |
MBSR versus wait list | Systolic BP | 2 | −5.351 | 0.313 | −15.738–5.035 | 0.000 | N/A |
MBSR versus active control conditions | Diastolic BP | 4 | −2.963 | 0.108 | −3.954–1.973 | 0.000 | No (intercept = 0.748, t(2) = 0.991, p = 0.213) |
MBSR versus active control conditions | Systolic BP | 4 | −3.218 | 0.197 | −8.304–1.818 | 20.111 | No (intercept = −0.123, t(2) = 0.062, p = 0.478) |
Moderators (multivariate meta-regression) | Outcome | B | z ( p -value) | ||||
Mean age | Diastolic BP | 6 | 0.175 | 0.94 (0.174) | |||
Percentage of females | −0.013 | −0.22 (0.411) | |||||
Percentage of participants on anti-hypertensive medications | −0.015 | −0.74 (.230) | |||||
Moderators (multivariate meta-regression) | Outcome | ||||||
Mean age | Systolic BP | 6 | 0.253 | 0.97 (0.165) | |||
Percentage of females | 0.043 | 0.50 (0.309) | |||||
Percentage of participants on anti-hypertensive medications | −0.750 | −2.73 (0.003) |
Notes: BP = blood pressure, k = number of studies included in the analysis, MBSR = mindfulness-based stress reduction, MD = mean difference, CI = confidence interval, N/A = not applicable due to the small number of studies.