Figure 2.

DMG-gold increased energy expenditure in high-fat diet (HFD)-fed animals. Oxygen consumption (VO₂) (A) and carbon dioxide production (VCO₂) (B), respiratory quotient (RQ) (VCO₂/VO₂) (C) and energy expenditure (EE) (D) were determined at the end of the experimental period by an open-circuit calorimeter (n = 7 each group). Data are presented as means ± SEM. CTR: control, HFD: high-fat diet, DMG: DMG-gold. Different superscripted letters on the histograms (a,b,c) indicate significantly different average values, p < 0.05.