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Tobramycin and vancomycin exposure via antibiotic administration methods to the system at 2, 12, 24 and 48 h. N = 4 replicates for Spacerv+t and CSBv+tplusSpacerv+t and 3 for VP; geometric mean ± 1 SE. (* p < 0.05, ** p < 0.01, *** p < 0.001). The same data shown on a linear Y-axis scale are available in supplemental material (Figure S1).
