Table 2.

All adverse events (AE) grade ≥3.

Toxicity	Grade III/IV		Grade V
	AE	Affected Patients (%)	AE	Affected Patients (%)
Increased alanine aminotransferase	11	3 (12%)	0	0 (0%)
Increased aspartate aminotransferase	3	1 (4%)	0	0 (0%)
Allergic reaction	1	1 (4%)	0	0 (0%)
Reduced general condition	2	2 (8%)	0	0 (0%)
Anemia	1	1 (4%)	0	0 (0%)
Arterial hypertension	7	2 (8%)	0	0 (0%)
Dehydration	2	1 (4%)	0	0 (0%)
Increased gamma-glutamyl transferase	6	1 (4%)	0	0 (0%)
Hepatic failure	0	0	1	1 (4%)
Anorexia	1	1 (4%)	0	0 (0%)
Catheter-related infection	1	1 (4%)	0	0 (0%)
Leukopenia	20	3 (12%)	0	0 (0%)
Fatigue	5	2 (8%)	0	0 (0%)
Neutropenia	16	3 (12%)	0	0 (0%)
Pneumothorax	1	1 (4%)	0	0 (0%)
Pleuritic pain	1	1 (4%)	0	0 (0%)
Back pain	5	2 (8%)	0	0 (0%)