Table 2.
The histopathological grades of myocardial injury in rats. I—ISOPRENALINE, ILN—ISOPRENALINE +L-NAME, IC—ISOPRENALINE + 4′-CHLORODIAZEPAM, ICLN—ISOPRENALINE +4′-CHLORODIAZEPAM + L-NAME. Fisher’s exact test: *—p < 0.05 vs. I, ^—p < 0.05 vs. IC.
| Grade 0 | Grade 1 | Grade 2 | Grade 3 | Σ | |
|---|---|---|---|---|---|
| I | 0 (0%) | 0 (0%) | 1 (20%) | 4 (80%) | 5 (100%) |
| ILN | 0 (0%) | 0 (0%) | 3 (75%) | 1 (25%) | 4 (100%) |
| IC * | 4 (80%) | 1 (20%) | 0 (0%) | 0 (0%) | 5 (100%) |
| ICLN ^ | 0 (0%) | 0 (0%) | 2 (50%) | 2 (50%) | 4 (100%) |
| Σ | 4 (22.2%) | 1 (5.6%) | 6 (33.3%) | 7 (38.9%) | 18 (100%) |
Grade 0—no changes; Grade 1—mild–focal myocyte damage or small multifocal degeneration with a slight degree of inflammatory process; Grade 2—moderate–extensive myofibrillar degeneration and/or diffuse inflammatory process; Grade 3—severe–necrosis with a diffuse inflammatory process.