Table 1.

Overview of results obtained from the physicochemical characterization of curcumin-loaded smartFilms, bulk- and nanosuspensions.

	SmartFilms			Bulk Suspension Non-Diluted			Nanosuspension Non-Diluted			Bulk Suspension Diluted			Nanosuspension Diluted
curcumin content [µg] in formulation	684	±	16	2098 *	±	41	1946 *	±	48	574 *	±	99	614 *	±	11
z-average [nm]	n.a.			n.a.			217	±	0.1	n.a.			205	±	0.1
PDI							0.31	±	0.02				0.35	±	0.02
d(v)0.1 [µm]				11	±	0.5	0.02	±	0.0	8	±	0.3	0.02	±	0.0
d(v)0.5 [µm]				45	±	7	0.1	±	0.0	24	±	2	0.1	±	0.0
d(v)0.9 [µm]				153	±	58	0.2	±	0.0	65	±	9	0.2	±	0.0
d(v)0.95 [µm]				188	±	77	0.5	±	0.0	84	±	15	0.5	±	0.0
d(v)0.99 [µm]				251	±	113	2.5	±	0.2	130	±	32	2.2	±	0.1
amount of curcumin [µg/cm2] applied on skin	152			466			432			128			136

* Content of curcumin represents the amount of curcumin in 50 µL (corresponding volume of formulation applied on skin).