Table 1.
Frequency and demographic characteristics of anti-MD5 DM across various countries in adults and children
| Country | Year | Study design | N | Prevalence of anti MDA-5 (%) | Mean age (SD) | Women (%) |
|---|---|---|---|---|---|---|
| Japan [8] | 2005 | R | 42 | 19 | – | – |
| Japan [44] | 2012 | R | 79 DM | 22 | 55 (13) | 88 |
| Japan [102] | 2012 | R | 27 MDA5 DM | – | 48 (13) | 74 |
| China [9] | 2013 | P | 43 DM | 60 | 46 (13) | 40 |
| Korea [58] | 2010 | R | 38 DM | 24 | 46 (16) | 55 |
| Italy [47] | 2014 | R | 34 DM | 15 | 54 (13) | 60 |
| Spain [50] | 2013 | R | 117 DM | 12 | 47.8 (11) | 64 |
| France [51] | 2020 | R | 121 MDA5 DM | – | Median 49 (34–58) | 67 |
| USA (Stanford) [52] | 2011 | R | 77 | 13 | 51 (9) | 88 |
| USA (Pittsburgh) [49, 103] | 2016 | R | 122 DM | 13 | 43 (18.5) | 56 |
| USA (Hopkins) [46] | 2013 | R | 160 DM | 7 | 41.4 | – |
| India [104] | 2020 | P | 83 DM | 17 | – | 72.7 |
| Canada [75] (70% Asians) | 2019 | R | 21 MDA5 DM | – | 52 (21–69) | 57 |
| UK [105] | 2014 | R | 285 JDM | 7 | 6.3 (4–10) | – |
| USA, Canada [106] | 2020 | R | 453 JIIM | 7.7 | Median 8.7 | – |
| France [40] | 2020 | R | 64 JIIM | 20 | 9 (2–14) | 60 |
| India [104] | 2020 | P | 36 JDM | 11 | – | – |
MDA5 Melanoma Differentiation Associated gene 5, DM Dermatomyositis, P Prospective, R Retrospective, USA United Sates of America, UK United Kingdom, – data unavailable