Figure 5.

Effect of HW-Pm on NF-κB activation. The assay was performed using a human monocytic cell line, stably transfected (U937-3xB-LUC reporter cell) with a luciferase reporter containing three NF-κB-binding sites. LPS (100 ng/mL) and IFN-γ (5 ng/mL) were used as positive controls for stimulation. L-NAME was tested at 100 µM. Means without the same letter are significantly different at the 5% level according to a one-way ANOVA test followed by a Tukey test (n = 3).