Table 2.

Complete Blood Count.

	Pre	d (95% CI)	Day 45	d (95% CI)	Day 90	d (95% CI)	p-Value
WBC (K/uL)
BHB	6.62 ± 1.74	0.62(−2.81, 0.60)	6.33 ± 1.14	0.62(−2.75, 0.66)	6.48 ± 1.22	0.04 (−1.65, 1.76)	0.0999
PLA	7.72 ± 1.81		7.38 ± 2.11		6.43 ± 1.61
RBC (M/uL)
BHB	4.75 ± 0.23	0.06(−0.30, 0.33)	4.79 ± 0.28	0.25(−0.24, 0.40)	4.71 ± 0.19	0.39(−0.42, 0.21)	0.0620
PLA	4.73 ± 0.43		4.71 ± 0.35		4.81 ± 0.31
Hemoglobin (g/dL)
BHB	14.12 ± 0.49	1.04(0.03, 1.54)	14.20 ± 0.49	1.32(0.24, 1.75)	13.98 ± 0.55	0.88(−0.16, 1.35)	0.1194
PLA	13.33 ± 0.96		13.21 ± 0.94		13.38 ± 0.79
Hematocrit (%)
BHB	41.58 ± 1.23	0.41(−1.21, 2.98)	41.88 ± 1.69	0.66(−0.74, 3.45)	40.63 ± 1.91	0.45(−1.27, 2.92)	0.7144
PLA	40.70 ± 2.77		40.52 ± 2.37		39.8 ± 1.81
MCV (fl)
BHB	87.83 ± 2.66	0.32(−3.58, 6.64)	87.50 ± 3.92	0.18(−4.21, 6.01)	86.33 ± 4.09	0.64(−1.88, 8.34)	0.0830
PLA	86.30 ± 6.11		86.60 ± 6.08		83.10 ± 5.86
MCH (pg)
BHB	29.80 ± 1.72	0.62(−0.87, 3.77)	29.71 ± 1.36	0.65(−0.81, 3.83)	29.71 ± 1.30	0.94(−0.52, 4.12)	0.6868
PLA	28.35 ± 3.11		28.20 ± 3.00		27.91 ± 2.39
MCHC (g/dL)
BHB	33.98 ± 1.19	0.86(0.05, 2.34)	33.93 ± 0.54	1.30(0.19, 2.48)	34.41 ± 0.75	0.94(−0.36, 1.94)	0.5386
PLA	32.78 ± 1.58		32.60 ± 1.34		33.62 ± 0.92
RDW (%)
BHB	12.15 ± 0.55	0.97(−1.89, 0.19)	12.20 ± 0.45	0.78(−1.79, 0.29)	12.12 ± 0.49	0.65(−1.83, 0.26)	0.9048
PLA	13.00 ± 1.11		12.95 ± 1.29		12.90 ± 1.64
Platelets (k/uL)
BHB	305.58 ± 53.63	0.10(−68.45, 54.62)	282.42 ± 42.79	0.40(−81.02, 42.05)	293.83 ± 51.58	0.17(−70.80, 52.27)	0.5519
PLA	312.50 ± 81.45		302.9 ± 59.23		303.10 ± 59.59

Data reported in mean and standard deviation. p-value is from group by time interaction effect. WBC: White blood Cell, RBC: Red Blood Cell, MCV: Mean Cell Volume, MCH: Mean Cell Hemoglobin, MCHC: Mean Cell Hemoglobin Concentration, RDW: Red Cell Distribution Width. 95% CI = 95% confidence interval of the mean difference between groups. d = Cohen’s d between-group effect size [(BHB-PLA)/SD_pooled].