Table 3.

Automated Differential Cell Count.

	Pre	d (95% CI)	Day 45	d (95% CI)	Day 90	d (95% CI)	p-Value
Neutrophils (%)
BHB	47.33 ± 7.02	1.04(−16.11, −0.03)	53.17 ± 8.01	0.28(−10.47, 5.61)	47.08 ± 6.56	0.82(−13.36, 2.72)	0.3080
PLA	55.40 ± 8.41		55.60 ± 9.18		52.40 ± 6.42
Lymphocytes (%)
BHB	40.67 ± 7.83	0.77(−1.70, 13.83)	33.92 ± 8.13	0.06(−7.35, 8.18)	40.83 ± 7.46	0.83(−2.63, 12.90)	0.2219
PLA	34.60 ± 8.03		33.50 ± 7.19		35.70 ± 4.59
Monocytes (%)
BHB	8.42 ± 1.44	1.13(−0.08, 2.92)	9.42 ± 1.68	1.30(0.62, 3.62)	8.67 ± 1.37	0.43(−0.93, 2.07)	0.0583
PLA	7.00 ± 1.05		7.30 ± 1.57		8.10 ± 1.29
Eosionophil (%)
BHB	2.67 ± 1.07	0.19(−1.77, 2.30)	2.58 ± 1.68	0.17(−2.45, 1.62)	2.42 ± 1.44	0.25(−2.52, 1.55)	0.2503
PLA	2.40 ± 1.71		3.00 ± 3.06		2.90 ± 2.29
Basophil (%)
BHB	0.92 ± 0.29	0.98(0.02, 0.81)	0.92 ± 0.29	0.98(0.02, 0.81)	1.00 ± 0.00	0.67(−0.20, 0.60)	0.3695
PLA	0.50 ± 0.53		0.50 ± 0.53		0.80 ± 0.42
Granulocytes (%)
BHB	0.00 ± 0.00	0.44(0.00, 0.00)	0.00 ± 0.00	0.44(0.00, 0.00)	0.00 ± 0.00	0.44(0.00, 0.00)	-
PLA	0.10 ± 0.32		0.10 ± 0.32		0.10 ± 0.32
Neutrophils (k/uL)
BHB	3.18 ± 1.21	0.88(−2.54, 0.17)	3.43 ± 1.10	0.51(−2.15, 0.56)	3.03 ± 0.64	0.40(−1.73, 0.98)	0.2945
PLA	4.36 ± 1.47		4.22 ± 1.92		3.41 ± 1.17
Lymphocytes (k/uL)
BHB	2.65 ± 0.74	0.06(−0.57, 0.65)	2.11 ± 0.32	0.79(−0.89, 0.33)	2.68 ± 0.77	0.64(−0.21, 1.00)	0.0644
PLA	2.61 ± 0.60		2.39 ± 0.39		2.28 ± 0.43
Monocytes (k/uL)
BHB	0.54 ± 0.14	0.00(−0.15, 0.15)	0.61 ± 0.15	0.57(−0.07, 0.23)	0.58 ± 0.14	0.48(−0.09, 0.22)	0.3383
PLA	0.54 ± 0.16		0.53 ± 0.13		0.51 ± 0.15
Eosionophil (k/uL)
BHB	0.18 ± 0.09	0.07(−0.15, 0.14)	0.15 ± 0.09	0.49(−0.21, 0.07)	0.18 ± 0.14	0.00(−0.14, 0.15)	0.0716
PLA	0.19 ± 0.17		0.22 ± 0.18		0.18 ± 0.13
Basophil (k/uL)
BHB	0.05 ± 0.05	0.2(−0.04, 0.06)	0.03 ± 0.05	0.00(−0.05, 0.06)	0.06 ± 0.05	0.2(−0.05, 0.06)	0.9618
PLA	0.04 ± 0.05		0.03 ± 0.05		0.05 ± 0.05
Granulocytes (k/uL)
BHB	0.00 ± 0.00	0.00(−0.01, 0.01)	0.00 ± 0.00	0.47(−0.02, 0.01)	0.00 ± 0.00	0.00(−0.01, 0.01)	0.3047
PLA	0.00 ± 0.00		0.01 ± 0.03		0.00 ± 0.00

Data reported in mean and standard deviation. p-value is from group by time interaction effect. 95% CI = 95% confidence interval of the mean difference between groups. d = Cohen’s d between-group effect size [(BHB-PLA)/SD_pooled].