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. 2021 Mar 10;12(3):395. doi: 10.3390/genes12030395

Figure 2.

Figure 2

Regulation of sister chromatid cohesion by the lncRNA CONCR. CONCR transcription is directly activated by Myc in a p53-deficient background. CONCR enhances the DDX11 catalytic activity, promoting sister chromatid cohesion establishment at the replication forks. CONCR knockdown causes sister chromatid cohesion loss.