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. 2021 Mar 10;13(3):365. doi: 10.3390/pharmaceutics13030365

Figure 6.

Figure 6

Antitumor efficacy of ACPP conjugated resiquimod. (A) Mice with B16 tumors intra-tumorally (IT) injected with free resiquimod. Mouse survival plotted and statistical significances calculated using Log-rank (Mantel–Cox) test. (B) Mice with B16 tumors treated IT with free resiquimod or ACPP conjugated resiquimod given IT or intravenously (IV). Tumors measured twice a week and plotted as mean tumor volume ± SEM. Statistical significances calculated using two-way ANOVA. * p < 0.05, ** p < 0.01.