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. 2021 Mar 5;10(3):396. doi: 10.3390/antiox10030396

Figure 4.

Figure 4

Ramipril limits vascular inflammation in chronic ischemic heart failure by attenuating myeloid cell infiltration. (A) Flow cytometry quantification of aortic tissue 28 days after MI vs. sham; left: representative FACS plots, right: quantification of leucocytes (CD45+), myeloid cells (CD45+CD11b+) and monocytes (CD45+CD11b+Ly6G-Ly6Chigh/low), n = 3–8 mice per group, mean + SEM, n = 3–8 mice per group; (B) mRNA expression of aortic tissue of Ccl-2, iNOS (Nos2), eNOS and TNFalpha 28 days after MI vs. sham (+Ramipril); mean + SEM, 1-way ANOVA or Kruskal–Wallis test with Dunn’s multiple comparisons test. * p < 0.05, ** p < 0.01.