Table 5.

ANOVA results for all responses.

Variable	Parameter
	p-Value	R 2	Lack of Fit
Y1: Content (%)	0.092	0.6820	0.165
X1: Polymer ratio	0.153
X2: Barrel Temp.	0.110
X1·X1	0.023
X2·X2	0.388
X1·X2	0.540
Regression equation
Y1 = −246 + 0.9X1 + 3.13X2 − 2.397X1·X1 − 0.000762X2·X2 + 0.070X1·X2
Y2: Dissolution rate (%)—SGF, 2 h	0.000	0.9507	0.367
X1: Polymer ratio	0.000
X2: Barrel Temp.	0.146
X1·X1	0.002
X2·X2	0.002
X1·X2	0.506
Regression equation
Y2 = −2283 + 19.7X1 + 2177X2 − 5.22X1·X1 − 0.0522X2·X2 + 0.103X1·X2
Y3: Dissolution rate (%)—SGF, 6 h	0.000	0.9628	0.018
X1: Polymer ratio	0.000
X2: Barrel Temp.	0.002
X1·X1	0.006
X2·X2	0.008
X1·X2	0.199
Regression equation
Y3 = −2184 + 86.3X1 + 19.54X2 − 4.59X1·1 − 0.0437X2·X2 − 0.221X1·X2
Y4: Dissolution rate (%)—SIF, 2 h	0.001	0.9344	0.353
X1: Polymer ratio	0.000
X2: Barrel Temp.	0.100
X1·X1	0.017
X2·X2	0.043
X1·X2	0.353
Regression equation
Y4 = −1382 + 40.0X1 + 12.89X2 − 3.77X1·X1 − 0.0299X2·X2 − 0.034X1·X2
Y5: Dissolution rate (%)—SIF, 6 h	0.000	0.9668	0.057
X1: Polymer ratio	0.000
X2: Barrel Temp.	0.025
X1·X1	0.005
X2·X2	0.231
X1·X2	0.046
Regression equation
Y5 = −866 + 107.8X1 + 6.99X2 − 4.22X1·X1 − 0.0136X2·X2 − 0.332X1·X2