Table 2.

Characteristics of genetic variants to influence 3GO risk selected by genome-wide association study (GWAS) in a Korean city hospital-based cohort.

Chr a	SNP b	Position	Mi c	Ma d	OR e	p_Adjust f	MAF g	p_HWE h	Gene	Functional Consequence
11	rs2237892	2839751	T	C	0.8155	1.41 × 10−6	0.3755	0.3933	KCNQ1	intron variant
11	rs2075291	116661392	A	C	1.585	2.17 × 10−11	0.0793	0.3655	ZPR1	upstream transcript variant
11	rs662799	116663707	G	A	1.355	2.90 × 10−12	0.2988	0.2874	APOA5	upstream transcript variant
11	rs5072	116707583	A	G	1.202	7.49 × 10−6	0.3593	0.8018	APOA1	intron variant
11	rs151139277	116753093	T	C	1.875	2.85 × 10−7	0.0192	0.7412	SIK3	downstream transcript variant

^a Chromosome; ^b Single nucleotide polymorphism; ^c Minor allele of haplotype; ^d Major allele of haplotype; ^e Odds ratio of each SNP for 3GO risk; ^f p-value for ORs after adjusting for age, gender, residence area, and BMI; ^g Minor allele frequency; ^h Hardy–Weinberg equilibrium.