Table 4.

Adjusted odds ratios for the risk of 3GO and related parameters according to the allele of the haplotype of 11q23 loci after covariate adjustments.

	Model 1			Model 2
	Major (n = 14,930)	Heterozygote (n = 13,862)	Minor (n = 1102)	Heterozygote (n = 13,862)	Minor (n = 1102)
3GO	1	1.435 (1.274–1.616) ***	2.938 (2.291–3.768) ***	1.251 (1.009–1.548) *	3.230 (2.062–5.061) ***
BMI	1	0.959 (0.907–1.014)	0.762 (0.651–0.892) **	0.965 (0.910–1.024)	0.757 (0.541–0.893) ***
Waist circumference	1	1.071 (0.966–1.191)	0.791 (0.578–1.082)	1.019 (0.849–1.223)	0.709 (0.401–1.256)
SBP	1	1.134 (1.014–1.268) *	1.689 (1.307–2.183) ***	1.090 (0.877–1.354)	2.135 (1.328–3.432) **
DBP	1	1.171 (1.022–1.342) *	1.435 (1.029~2.002) *	1.188 (0.949–1.487)	1.039 (0.548–1.971)
BP	1	1.171 (1.022~1.342) *	1.435 (1.029~2.002) *	1.121 (0.943~1.333)	1.487 (0.966~2.289)
Serum glucose	1	1.123 (1.052~1.199)	1.478 (1.255~1.740) ***	1.141 (0.888~1.466)	2.138 (1.222~3.742) **
HbA1c	1	1.374 (1.214–1.556) *	2.670 (2.056–3.467) ***	1.365 (1.190–1.544) *	2.688 (2.048–3.529) ***
Serum total cholesterol	1	1.115 (1.025–1.212)	1.448 (1.183–1.771) **	0.940 (0.593–1.490)	3.095 (1.374–6.972) **
Serum HDL	1	1.320 (1.239–1.406) ***	2.339 (2.020–2.708) ***	1.318 (0.975–1.781) *	3.196 (1.761–5.801) ***
Serum TG	1	1.530 (1.421–1.648)	2.744 (2.330–3.230) ***	2.212 (1.535–3.187) ***	3.658 (1.755–7.624) ***

Values represent odds ratio and 95% confidence intervals after adjusting for covariates age, gender, residence area, and BMI (model 1) and covariates for model 1, plus intake of energy, alcohol, and coffee, physical activity (model 2). Haplotype generated with 5 single nucleotide polymorphisms (SNPs) was divided into 3 categories (0–3, 4–6, and 7–10) by tertiles as the major, heterozygote, and minor alleles, respectively. Haplotype’s major allele was the reference for both model 1 and model 2. * Significantly different from the major allele in logistic regression analysis at p < 0.05, ** p < 0.01, *** p < 0.001.