Table 3.

Predictive factors of radiographic progression by using univariate and multivariate linear regression analyses in patients with seronegative rheumatoid arthritis.

	Univariable		Multivariable 1
	β ± SE	p-Value	β ± SE	p-Value
Sex	0.47 ± 1.20	0.69	n.s.	n.s.
Age at diagnosis	0.11 ± 0.04	0.61	n.s.	n.s.
Symptom duration at diagnosis	0.29 ± 0.13	0.02	0.08 ± 0.09	0.42
Smoking at diagnosis	−0.78 ± 1.60	0.63	n.s.	n.s.
Morning stiffness at diagnosis	0.48 ± 0.32	0.71	n.s.	n.s.
Number of active synovitis at diagnosis	0.03 ± 0.08	0.64	n.s.	n.s.
CRP at diagnosis	1.19 ± 0.21	0.34	n.s.	n.s.
Joint erosion at diagnosis	12.61 ± 1.09	<0.001	6.50 ± 1.84	0.001
SvdH score at diagnosis	0.21 ± 0.02	<0.001	0.12 ± 0.02	<0.001

¹ Adjusted for sex, age, number of active synovitis, symptom duration, CRP, joint erosion, SvdH score at diagnosis. Smoking status was not included multivariate linear regression analysis because of missing values. β, unstandardized regression coefficient; SE, standard error; n.s., nonsignificant; CRP, C-reactive protein; SvdH, the Sharp van der Heijde.