Table A2.
Information of Concomitant Medications Targeting on Central Nervous System.
| Level | Aripiprazole | Haloperidol | Lurasidone | Olanzapine | Perphenazine | Quetiapine | Risperidone | Ziprasidone | p | |
|---|---|---|---|---|---|---|---|---|---|---|
| n | 982 | 822 | 209 | 510 | 427 | 1429 | 693 | 222 | ||
| Acetaminophen (%) | 0 | 673 (68.5) | 230 (28.0) | 144 (68.9) | 303 (59.4) | 75 (17.6) | 850 (59.5) | 461 (66.5) | 144 (64.9) | <0.001 |
| 1 | 309 (31.5) | 592 (72.0) | 65 (31.1) | 207 (40.6) | 352 (82.4) | 579 (40.5) | 232 (33.5) | 78 (35.1) | ||
| Almotriptan (%) | 0 | 982 (100.0) | 821 (99.9) | 209 (100.0) | 510 (100.0) | 427 (100.0) | 1429 (100.0) | 693 (100.0) | 222 (100.0) | 0.606 |
| 1 | 0 (0.0) | 1 (0.1) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | ||
| Alprazolam (%) | 0 | 910 (92.7) | 760 (92.5) | 193 (92.3) | 461 (90.4) | 386 (90.4) | 1285 (89.9) | 650 (93.8) | 210 (94.6) | 0.022 |
| 1 | 72 (7.3) | 62 (7.5) | 16 (7.7) | 49 (9.6) | 41 (9.6) | 144 (10.1) | 43 (6.2) | 12 (5.4) | ||
| Amitriptyline (%) | 0 | 932 (94.9) | 783 (95.3) | 195 (93.3) | 489 (95.9) | 407 (95.3) | 1379 (96.5) | 666 (96.1) | 216 (97.3) | 0.259 |
| 1 | 50 (5.1) | 39 (4.7) | 14 (6.7) | 21 (4.1) | 20 (4.7) | 50 (3.5) | 27 (3.9) | 6 (2.7) | ||
| Amphetamine (%) | 0 | 930 (94.7) | 809 (98.4) | 202 (96.7) | 493 (96.7) | 418 (97.9) | 1389 (97.2) | 665 (96.0) | 216 (97.3) | 0.001 |
| 1 | 52 (5.3) | 13 (1.6) | 7 (3.3) | 17 (3.3) | 9 (2.1) | 40 (2.8) | 28 (4.0) | 6 (2.7) | ||
| Aripiprazole (%) | 0 | 0 (0.0) | 820 (99.8) | 209 (100.0) | 509 (99.8) | 427 (100.0) | 1426 (99.8) | 690 (99.6) | 222 (100.0) | <0.001 |
| 1 | 982 (100.0) | 2 (0.2) | 0 (0.0) | 1 (0.2) | 0 (0.0) | 3 (0.2) | 3 (0.4) | 0 (0.0) | ||
| Armodafinil (%) | 0 | 981 (99.9) | 822 (100.0) | 209 (100.0) | 510 (100.0) | 426 (99.8) | 1427 (99.9) | 692 (99.9) | 222 (100.0) | 0.88 |
| 1 | 1 (0.1) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (0.2) | 2 (0.1) | 1 (0.1) | 0 (0.0) | ||
| Aspirin (%) | 0 | 918 (93.5) | 664 (80.8) | 197 (94.3) | 442 (86.7) | 377 (88.3) | 1273 (89.1) | 625 (90.2) | 204 (91.9) | <0.001 |
| 1 | 64 (6.5) | 158 (19.2) | 12 (5.7) | 68 (13.3) | 50 (11.7) | 156 (10.9) | 68 (9.8) | 18 (8.1) | ||
| Atomoxetine (%) | 0 | 960 (97.8) | 818 (99.5) | 205 (98.1) | 503 (98.6) | 424 (99.3) | 1405 (98.3) | 680 (98.1) | 220 (99.1) | 0.07 |
| 1 | 22 (2.2) | 4 (0.5) | 4 (1.9) | 7 (1.4) | 3 (0.7) | 24 (1.7) | 13 (1.9) | 2 (0.9) | ||
| Atropine (%) | 0 | 976 (99.4) | 753 (91.6) | 205 (98.1) | 496 (97.3) | 417 (97.7) | 1387 (97.1) | 680 (98.1) | 217 (97.7) | <0.001 |
| 1 | 6 (0.6) | 69 (8.4) | 4 (1.9) | 14 (2.7) | 10 (2.3) | 42 (2.9) | 13 (1.9) | 5 (2.3) | ||
| Benzoate (%) | 0 | 963 (98.1) | 810 (98.5) | 206 (98.6) | 495 (97.1) | 419 (98.1) | 1409 (98.6) | 683 (98.6) | 218 (98.2) | 0.488 |
| 1 | 19 (1.9) | 12 (1.5) | 3 (1.4) | 15 (2.9) | 8 (1.9) | 20 (1.4) | 10 (1.4) | 4 (1.8) | ||
| Brompheniramine (%) | 0 | 981 (99.9) | 822 (100.0) | 209 (100.0) | 510 (100.0) | 427 (100.0) | 1427 (99.9) | 693 (100.0) | 222 (100.0) | 0.809 |
| 1 | 1 (0.1) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 2 (0.1) | 0 (0.0) | 0 (0.0) | ||
| Buprenorphine (%) | 0 | 950 (96.7) | 803 (97.7) | 203 (97.1) | 494 (96.9) | 418 (97.9) | 1381 (96.6) | 676 (97.5) | 212 (95.5) | 0.552 |
| 1 | 32 (3.3) | 19 (2.3) | 6 (2.9) | 16 (3.1) | 9 (2.1) | 48 (3.4) | 17 (2.5) | 10 (4.5) | ||
| Bupropion (%) | 0 | 834 (84.9) | 755 (91.8) | 183 (87.6) | 465 (91.2) | 382 (89.5) | 1286 (90.0) | 625 (90.2) | 192 (86.5) | <0.001 |
| 1 | 148 (15.1) | 67 (8.2) | 26 (12.4) | 45 (8.8) | 45 (10.5) | 143 (10.0) | 68 (9.8) | 30 (13.5) | ||
| Buspirone (%) | 0 | 904 (92.1) | 783 (95.3) | 183 (87.6) | 474 (92.9) | 406 (95.1) | 1312 (91.8) | 639 (92.2) | 204 (91.9) | 0.002 |
| 1 | 78 (7.9) | 39 (4.7) | 26 (12.4) | 36 (7.1) | 21 (4.9) | 117 (8.2) | 54 (7.8) | 18 (8.1) | ||
| Butalbital (%) | 0 | 980 (99.8) | 822 (100.0) | 209 (100.0) | 510 (100.0) | 427 (100.0) | 1428 (99.9) | 692 (99.9) | 222 (100.0) | 0.753 |
| 1 | 2 (0.2) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (0.1) | 1 (0.1) | 0 (0.0) | ||
| Butorphanol (%) | 0 | 981 (99.9) | 819 (99.6) | 209 (100.0) | 510 (100.0) | 427 (100.0) | 1428 (99.9) | 692 (99.9) | 222 (100.0) | 0.488 |
| 1 | 1 (0.1) | 3 (0.4) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (0.1) | 1 (0.1) | 0 (0.0) | ||
| Caffeine (%) | 0 | 972 (99.0) | 811 (98.7) | 206 (98.6) | 498 (97.6) | 418 (97.9) | 1411 (98.7) | 686 (99.0) | 220 (99.1) | 0.38 |
| 1 | 10 (1.0) | 11 (1.3) | 3 (1.4) | 12 (2.4) | 9 (2.1) | 18 (1.3) | 7 (1.0) | 2 (0.9) | ||
| Calcium Carbonate (%) | 0 | 963 (98.1) | 806 (98.1) | 207 (99.0) | 499 (97.8) | 403 (94.4) | 1400 (98.0) | 677 (97.7) | 218 (98.2) | 0.001 |
| 1 | 19 (1.9) | 16 (1.9) | 2 (1.0) | 11 (2.2) | 24 (5.6) | 29 (2.0) | 16 (2.3) | 4 (1.8) | ||
| Carbamazepine (%) | 0 | 968 (98.6) | 811 (98.7) | 203 (97.1) | 497 (97.5) | 424 (99.3) | 1411 (98.7) | 673 (97.1) | 218 (98.2) | 0.033 |
| 1 | 14 (1.4) | 11 (1.3) | 6 (2.9) | 13 (2.5) | 3 (0.7) | 18 (1.3) | 20 (2.9) | 4 (1.8) | ||
| Carbidopa (%) | 0 | 982 (100.0) | 822 (100.0) | 209 (100.0) | 509 (99.8) | 423 (99.1) | 1426 (99.8) | 692 (99.9) | 221 (99.5) | 0.015 |
| 1 | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (0.2) | 4 (0.9) | 3 (0.2) | 1 (0.1) | 1 (0.5) | ||
| Carisoprodol (%) | 0 | 972 (99.0) | 809 (98.4) | 207 (99.0) | 504 (98.8) | 421 (98.6) | 1410 (98.7) | 685 (98.8) | 217 (97.7) | 0.877 |
| 1 | 10 (1.0) | 13 (1.6) | 2 (1.0) | 6 (1.2) | 6 (1.4) | 19 (1.3) | 8 (1.2) | 5 (2.3) | ||
| Chlordiazepoxide (%) | 0 | 980 (99.8) | 807 (98.2) | 206 (98.6) | 506 (99.2) | 424 (99.3) | 1410 (98.7) | 681 (98.3) | 222 (100.0) | 0.011 |
| 1 | 2 (0.2) | 15 (1.8) | 3 (1.4) | 4 (0.8) | 3 (0.7) | 19 (1.3) | 12 (1.7) | 0 (0.0) | ||
| Chlorpheniramine (%) | 0 | 981 (99.9) | 822 (100.0) | 209 (100.0) | 510 (100.0) | 427 (100.0) | 1429 (100.0) | 691 (99.7) | 222 (100.0) | 0.254 |
| 1 | 1 (0.1) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 2 (0.3) | 0 (0.0) | ||
| Chlorpromazine (%) | 0 | 981 (99.9) | 822 (100.0) | 209 (100.0) | 510 (100.0) | 427 (100.0) | 1429 (100.0) | 693 (100.0) | 222 (100.0) | 0.734 |
| 1 | 1 (0.1) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | ||
| Chlorthalidone (%) | 0 | 978 (99.6) | 821 (99.9) | 209 (100.0) | 508 (99.6) | 426 (99.8) | 1424 (99.7) | 692 (99.9) | 222 (100.0) | 0.82 |
| 1 | 4 (0.4) | 1 (0.1) | 0 (0.0) | 2 (0.4) | 1 (0.2) | 5 (0.3) | 1 (0.1) | 0 (0.0) | ||
| Choline (%) | 0 | 956 (97.4) | 636 (77.4) | 203 (97.1) | 480 (94.1) | 260 (60.9) | 1369 (95.8) | 669 (96.5) | 216 (97.3) | <0.001 |
| 1 | 26 (2.6) | 186 (22.6) | 6 (2.9) | 30 (5.9) | 167 (39.1) | 60 (4.2) | 24 (3.5) | 6 (2.7) | ||
| Citalopram (%) | 0 | 821 (83.6) | 724 (88.1) | 179 (85.6) | 435 (85.3) | 384 (89.9) | 1193 (83.5) | 576 (83.1) | 200 (90.1) | 0.001 |
| 1 | 161 (16.4) | 98 (11.9) | 30 (14.4) | 75 (14.7) | 43 (10.1) | 236 (16.5) | 117 (16.9) | 22 (9.9) | ||
| Clidinium (%) | 0 | 978 (99.6) | 816 (99.3) | 209 (100.0) | 507 (99.4) | 426 (99.8) | 1425 (99.7) | 692 (99.9) | 222 (100.0) | 0.444 |
| 1 | 4 (0.4) | 6 (0.7) | 0 (0.0) | 3 (0.6) | 1 (0.2) | 4 (0.3) | 1 (0.1) | 0 (0.0) | ||
| Clobazam (%) | 0 | 982 (100.0) | 822 (100.0) | 209 (100.0) | 509 (99.8) | 427 (100.0) | 1429 (100.0) | 693 (100.0) | 221 (99.5) | 0.034 |
| 1 | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (0.2) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (0.5) | ||
| Clomipramine (%) | 0 | 980 (99.8) | 822 (100.0) | 209 (100.0) | 509 (99.8) | 427 (100.0) | 1428 (99.9) | 691 (99.7) | 220 (99.1) | 0.094 |
| 1 | 2 (0.2) | 0 (0.0) | 0 (0.0) | 1 (0.2) | 0 (0.0) | 1 (0.1) | 2 (0.3) | 2 (0.9) | ||
| Clonazepam (%) | 0 | 809 (82.4) | 730 (88.8) | 182 (87.1) | 423 (82.9) | 378 (88.5) | 1179 (82.5) | 587 (84.7) | 179 (80.6) | <0.001 |
| 1 | 173 (17.6) | 92 (11.2) | 27 (12.9) | 87 (17.1) | 49 (11.5) | 250 (17.5) | 106 (15.3) | 43 (19.4) | ||
| Clonidine (%) | 0 | 951 (96.8) | 755 (91.8) | 202 (96.7) | 465 (91.2) | 387 (90.6) | 1332 (93.2) | 641 (92.5) | 212 (95.5) | <0.001 |
| 1 | 31 (3.2) | 67 (8.2) | 7 (3.3) | 45 (8.8) | 40 (9.4) | 97 (6.8) | 52 (7.5) | 10 (4.5) | ||
| Clorazepate (%) | 0 | 981 (99.9) | 822 (100.0) | 209 (100.0) | 508 (99.6) | 427 (100.0) | 1428 (99.9) | 693 (100.0) | 222 (100.0) | 0.278 |
| 1 | 1 (0.1) | 0 (0.0) | 0 (0.0) | 2 (0.4) | 0 (0.0) | 1 (0.1) | 0 (0.0) | 0 (0.0) | ||
| Codeine (%) | 0 | 955 (97.3) | 785 (95.5) | 205 (98.1) | 496 (97.3) | 410 (96.0) | 1386 (97.0) | 677 (97.7) | 216 (97.3) | 0.208 |
| 1 | 27 (2.7) | 37 (4.5) | 4 (1.9) | 14 (2.7) | 17 (4.0) | 43 (3.0) | 16 (2.3) | 6 (2.7) | ||
| Desipramine (%) | 0 | 979 (99.7) | 822 (100.0) | 208 (99.5) | 509 (99.8) | 427 (100.0) | 1428 (99.9) | 693 (100.0) | 222 (100.0) | 0.278 |
| 1 | 3 (0.3) | 0 (0.0) | 1 (0.5) | 1 (0.2) | 0 (0.0) | 1 (0.1) | 0 (0.0) | 0 (0.0) | ||
| Desvenlafaxine (%) | 0 | 977 (99.5) | 817 (99.4) | 208 (99.5) | 509 (99.8) | 425 (99.5) | 1423 (99.6) | 688 (99.3) | 217 (97.7) | 0.062 |
| 1 | 5 (0.5) | 5 (0.6) | 1 (0.5) | 1 (0.2) | 2 (0.5) | 6 (0.4) | 5 (0.7) | 5 (2.3) | ||
| Dexmedetomidine (%) | 0 | 969 (98.7) | 698 (84.9) | 205 (98.1) | 496 (97.3) | 307 (71.9) | 1394 (97.6) | 687 (99.1) | 220 (99.1) | <0.001 |
| 1 | 13 (1.3) | 124 (15.1) | 4 (1.9) | 14 (2.7) | 120 (28.1) | 35 (2.4) | 6 (0.9) | 2 (0.9) | ||
| Dexmethylphenidate (%) | 0 | 978 (99.6) | 822 (100.0) | 209 (100.0) | 508 (99.6) | 427 (100.0) | 1428 (99.9) | 689 (99.4) | 220 (99.1) | 0.053 |
| 1 | 4 (0.4) | 0 (0.0) | 0 (0.0) | 2 (0.4) | 0 (0.0) | 1 (0.1) | 4 (0.6) | 2 (0.9) | ||
| Dextroamphetamine (%) | 0 | 930 (94.7) | 809 (98.4) | 202 (96.7) | 493 (96.7) | 418 (97.9) | 1389 (97.2) | 665 (96.0) | 216 (97.3) | 0.001 |
| 1 | 52 (5.3) | 13 (1.6) | 7 (3.3) | 17 (3.3) | 9 (2.1) | 40 (2.8) | 28 (4.0) | 6 (2.7) | ||
| Dextromethorphan (%) | 0 | 980 (99.8) | 816 (99.3) | 207 (99.0) | 509 (99.8) | 424 (99.3) | 1420 (99.4) | 690 (99.6) | 222 (100.0) | 0.477 |
| 1 | 2 (0.2) | 6 (0.7) | 2 (1.0) | 1 (0.2) | 3 (0.7) | 9 (0.6) | 3 (0.4) | 0 (0.0) | ||
| Diazepam (%) | 0 | 941 (95.8) | 755 (91.8) | 197 (94.3) | 485 (95.1) | 409 (95.8) | 1357 (95.0) | 662 (95.5) | 214 (96.4) | 0.006 |
| 1 | 41 (4.2) | 67 (8.2) | 12 (5.7) | 25 (4.9) | 18 (4.2) | 72 (5.0) | 31 (4.5) | 8 (3.6) | ||
| Dihydroergotamine (%) | 0 | 981 (99.9) | 817 (99.4) | 209 (100.0) | 503 (98.6) | 426 (99.8) | 1425 (99.7) | 692 (99.9) | 222 (100.0) | 0.004 |
| 1 | 1 (0.1) | 5 (0.6) | 0 (0.0) | 7 (1.4) | 1 (0.2) | 4 (0.3) | 1 (0.1) | 0 (0.0) | ||
| Dimenhydrinate (%) | 0 | 981 (99.9) | 817 (99.4) | 209 (100.0) | 509 (99.8) | 406 (95.1) | 1428 (99.9) | 693 (100.0) | 222 (100.0) | <0.001 |
| 1 | 1 (0.1) | 5 (0.6) | 0 (0.0) | 1 (0.2) | 21 (4.9) | 1 (0.1) | 0 (0.0) | 0 (0.0) | ||
| Diphenhydramine (%) | 0 | 925 (94.2) | 591 (71.9) | 195 (93.3) | 438 (85.9) | 350 (82.0) | 1289 (90.2) | 634 (91.5) | 206 (92.8) | <0.001 |
| 1 | 57 (5.8) | 231 (28.1) | 14 (6.7) | 72 (14.1) | 77 (18.0) | 140 (9.8) | 59 (8.5) | 16 (7.2) | ||
| Dipyridamole (%) | 0 | 982 (100.0) | 822 (100.0) | 209 (100.0) | 509 (99.8) | 426 (99.8) | 1428 (99.9) | 692 (99.9) | 222 (100.0) | 0.717 |
| 1 | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (0.2) | 1 (0.2) | 1 (0.1) | 1 (0.1) | 0 (0.0) | ||
| Donepezil (%) | 0 | 978 (99.6) | 818 (99.5) | 208 (99.5) | 509 (99.8) | 426 (99.8) | 1415 (99.0) | 683 (98.6) | 221 (99.5) | 0.079 |
| 1 | 4 (0.4) | 4 (0.5) | 1 (0.5) | 1 (0.2) | 1 (0.2) | 14 (1.0) | 10 (1.4) | 1 (0.5) | ||
| Doxepin (%) | 0 | 953 (97.0) | 795 (96.7) | 204 (97.6) | 495 (97.1) | 419 (98.1) | 1386 (97.0) | 677 (97.7) | 209 (94.1) | 0.197 |
| 1 | 29 (3.0) | 27 (3.3) | 5 (2.4) | 15 (2.9) | 8 (1.9) | 43 (3.0) | 16 (2.3) | 13 (5.9) | ||
| Doxylamine (%) | 0 | 982 (100.0) | 822 (100.0) | 208 (99.5) | 510 (100.0) | 427 (100.0) | 1426 (99.8) | 693 (100.0) | 221 (99.5) | 0.118 |
| 1 | 0 (0.0) | 0 (0.0) | 1 (0.5) | 0 (0.0) | 0 (0.0) | 3 (0.2) | 0 (0.0) | 1 (0.5) | ||
| Duloxetine (%) | 0 | 874 (89.0) | 766 (93.2) | 185 (88.5) | 455 (89.2) | 394 (92.3) | 1291 (90.3) | 652 (94.1) | 203 (91.4) | 0.002 |
| 1 | 108 (11.0) | 56 (6.8) | 24 (11.5) | 55 (10.8) | 33 (7.7) | 138 (9.7) | 41 (5.9) | 19 (8.6) | ||
| Eletriptan (%) | 0 | 982 (100.0) | 821 (99.9) | 209 (100.0) | 508 (99.6) | 425 (99.5) | 1428 (99.9) | 692 (99.9) | 222 (100.0) | 0.285 |
| 1 | 0 (0.0) | 1 (0.1) | 0 (0.0) | 2 (0.4) | 2 (0.5) | 1 (0.1) | 1 (0.1) | 0 (0.0) | ||
| Ergotamine (%) | 0 | 981 (99.9) | 817 (99.4) | 209 (100.0) | 502 (98.4) | 426 (99.8) | 1425 (99.7) | 692 (99.9) | 222 (100.0) | 0.001 |
| 1 | 1 (0.1) | 5 (0.6) | 0 (0.0) | 8 (1.6) | 1 (0.2) | 4 (0.3) | 1 (0.1) | 0 (0.0) | ||
| Escitalopram (%) | 0 | 903 (92.0) | 786 (95.6) | 193 (92.3) | 476 (93.3) | 409 (95.8) | 1336 (93.5) | 644 (92.9) | 211 (95.0) | 0.03 |
| 1 | 79 (8.0) | 36 (4.4) | 16 (7.7) | 34 (6.7) | 18 (4.2) | 93 (6.5) | 49 (7.1) | 11 (5.0) | ||
| Estazolam (%) | 0 | 982 (100.0) | 822 (100.0) | 209 (100.0) | 509 (99.8) | 427 (100.0) | 1429 (100.0) | 693 (100.0) | 222 (100.0) | 0.226 |
| 1 | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (0.2) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | ||
| Eszopiclone (%) | 0 | 977 (99.5) | 821 (99.9) | 208 (99.5) | 509 (99.8) | 425 (99.5) | 1423 (99.6) | 691 (99.7) | 220 (99.1) | 0.744 |
| 1 | 5 (0.5) | 1 (0.1) | 1 (0.5) | 1 (0.2) | 2 (0.5) | 6 (0.4) | 2 (0.3) | 2 (0.9) | ||
| Fentanyl (%) | 0 | 903 (92.0) | 436 (53.0) | 196 (93.8) | 434 (85.1) | 191 (44.7) | 1233 (86.3) | 616 (88.9) | 202 (91.0) | <0.001 |
| 1 | 79 (8.0) | 386 (47.0) | 13 (6.2) | 76 (14.9) | 236 (55.3) | 196 (13.7) | 77 (11.1) | 20 (9.0) | ||
| Fluoxetine (%) | 0 | 871 (88.7) | 761 (92.6) | 188 (90.0) | 440 (86.3) | 385 (90.2) | 1291 (90.3) | 603 (87.0) | 206 (92.8) | 0.002 |
| 1 | 111 (11.3) | 61 (7.4) | 21 (10.0) | 70 (13.7) | 42 (9.8) | 138 (9.7) | 90 (13.0) | 16 (7.2) | ||
| Fluphenazine (%) | 0 | 982 (100.0) | 820 (99.8) | 209 (100.0) | 510 (100.0) | 427 (100.0) | 1429 (100.0) | 693 (100.0) | 222 (100.0) | 0.144 |
| 1 | 0 (0.0) | 2 (0.2) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | ||
| Flurazepam (%) | 0 | 981 (99.9) | 822 (100.0) | 209 (100.0) | 509 (99.8) | 427 (100.0) | 1429 (100.0) | 693 (100.0) | 222 (100.0) | 0.553 |
| 1 | 1 (0.1) | 0 (0.0) | 0 (0.0) | 1 (0.2) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | ||
| Fluvoxamine (%) | 0 | 976 (99.4) | 818 (99.5) | 207 (99.0) | 506 (99.2) | 426 (99.8) | 1419 (99.3) | 689 (99.4) | 220 (99.1) | 0.94 |
| 1 | 6 (0.6) | 4 (0.5) | 2 (1.0) | 4 (0.8) | 1 (0.2) | 10 (0.7) | 4 (0.6) | 2 (0.9) | ||
| Frovatriptan (%) | 0 | 982 (100.0) | 822 (100.0) | 209 (100.0) | 510 (100.0) | 427 (100.0) | 1428 (99.9) | 692 (99.9) | 222 (100.0) | 0.817 |
| 1 | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (0.1) | 1 (0.1) | 0 (0.0) | ||
| Gabapentin (%) | 0 | 797 (81.2) | 605 (73.6) | 147 (70.3) | 384 (75.3) | 264 (61.8) | 1069 (74.8) | 564 (81.4) | 168 (75.7) | <0.001 |
| 1 | 185 (18.8) | 217 (26.4) | 62 (29.7) | 126 (24.7) | 163 (38.2) | 360 (25.2) | 129 (18.6) | 54 (24.3) | ||
| Galantamine (%) | 0 | 981 (99.9) | 822 (100.0) | 209 (100.0) | 510 (100.0) | 427 (100.0) | 1428 (99.9) | 693 (100.0) | 222 (100.0) | 0.923 |
| 1 | 1 (0.1) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (0.1) | 0 (0.0) | 0 (0.0) | ||
| Guaifenesin (%) | 0 | 963 (98.1) | 769 (93.6) | 202 (96.7) | 493 (96.7) | 421 (98.6) | 1370 (95.9) | 677 (97.7) | 217 (97.7) | <0.001 |
| 1 | 19 (1.9) | 53 (6.4) | 7 (3.3) | 17 (3.3) | 6 (1.4) | 59 (4.1) | 16 (2.3) | 5 (2.3) | ||
| Haloperidol (%) | 0 | 982 (100.0) | 0 (0.0) | 209 (100.0) | 510 (100.0) | 427 (100.0) | 1428 (99.9) | 693 (100.0) | 222 (100.0) | <0.001 |
| 1 | 0 (0.0) | 822 (100.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (0.1) | 0 (0.0) | 0 (0.0) | ||
| Homatropine (%) | 0 | 981 (99.9) | 816 (99.3) | 209 (100.0) | 505 (99.0) | 424 (99.3) | 1416 (99.1) | 690 (99.6) | 220 (99.1) | 0.223 |
| 1 | 1 (0.1) | 6 (0.7) | 0 (0.0) | 5 (1.0) | 3 (0.7) | 13 (0.9) | 3 (0.4) | 2 (0.9) | ||
| Hydrocodone (%) | 0 | 859 (87.5) | 682 (83.0) | 176 (84.2) | 451 (88.4) | 328 (76.8) | 1245 (87.1) | 612 (88.3) | 195 (87.8) | <0.001 |
| 1 | 123 (12.5) | 140 (17.0) | 33 (15.8) | 59 (11.6) | 99 (23.2) | 184 (12.9) | 81 (11.7) | 27 (12.2) | ||
| Hydromorphone (%) | 0 | 897 (91.3) | 418 (50.9) | 190 (90.9) | 430 (84.3) | 107 (25.1) | 1181 (82.6) | 613 (88.5) | 196 (88.3) | <0.001 |
| 1 | 85 (8.7) | 404 (49.1) | 19 (9.1) | 80 (15.7) | 320 (74.9) | 248 (17.4) | 80 (11.5) | 26 (11.7) | ||
| Hyoscyamine (%) | 0 | 976 (99.4) | 804 (97.8) | 207 (99.0) | 507 (99.4) | 419 (98.1) | 1422 (99.5) | 693 (100.0) | 220 (99.1) | <0.001 |
| 1 | 6 (0.6) | 18 (2.2) | 2 (1.0) | 3 (0.6) | 8 (1.9) | 7 (0.5) | 0 (0.0) | 2 (0.9) | ||
| Ibuprofen (%) | 0 | 840 (85.5) | 637 (77.5) | 167 (79.9) | 428 (83.9) | 274 (64.2) | 1173 (82.1) | 574 (82.8) | 189 (85.1) | <0.001 |
| 1 | 142 (14.5) | 185 (22.5) | 42 (20.1) | 82 (16.1) | 153 (35.8) | 256 (17.9) | 119 (17.2) | 33 (14.9) | ||
| Imipramine (%) | 0 | 979 (99.7) | 821 (99.9) | 207 (99.0) | 507 (99.4) | 426 (99.8) | 1418 (99.2) | 691 (99.7) | 222 (100.0) | 0.235 |
| 1 | 3 (0.3) | 1 (0.1) | 2 (1.0) | 3 (0.6) | 1 (0.2) | 11 (0.8) | 2 (0.3) | 0 (0.0) | ||
| Lacosamide (%) | 0 | 980 (99.8) | 819 (99.6) | 208 (99.5) | 508 (99.6) | 427 (100.0) | 1427 (99.9) | 691 (99.7) | 220 (99.1) | 0.48 |
| 1 | 2 (0.2) | 3 (0.4) | 1 (0.5) | 2 (0.4) | 0 (0.0) | 2 (0.1) | 2 (0.3) | 2 (0.9) | ||
| Lamotrigine (%) | 0 | 889 (90.5) | 784 (95.4) | 167 (79.9) | 459 (90.0) | 408 (95.6) | 1318 (92.2) | 628 (90.6) | 187 (84.2) | <0.001 |
| 1 | 93 (9.5) | 38 (4.6) | 42 (20.1) | 51 (10.0) | 19 (4.4) | 111 (7.8) | 65 (9.4) | 35 (15.8) | ||
| Levetiracetam (%) | 0 | 965 (98.3) | 773 (94.0) | 200 (95.7) | 485 (95.1) | 419 (98.1) | 1380 (96.6) | 680 (98.1) | 216 (97.3) | <0.001 |
| 1 | 17 (1.7) | 49 (6.0) | 9 (4.3) | 25 (4.9) | 8 (1.9) | 49 (3.4) | 13 (1.9) | 6 (2.7) | ||
| Levodopa (%) | 0 | 982 (100.0) | 822 (100.0) | 209 (100.0) | 509 (99.8) | 425 (99.5) | 1427 (99.9) | 692 (99.9) | 221 (99.5) | 0.316 |
| 1 | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (0.2) | 2 (0.5) | 2 (0.1) | 1 (0.1) | 1 (0.5) | ||
| Levomilnacipran (%) | 0 | 981 (99.9) | 822 (100.0) | 208 (99.5) | 509 (99.8) | 427 (100.0) | 1427 (99.9) | 689 (99.4) | 221 (99.5) | 0.177 |
| 1 | 1 (0.1) | 0 (0.0) | 1 (0.5) | 1 (0.2) | 0 (0.0) | 2 (0.1) | 4 (0.6) | 1 (0.5) | ||
| Lisdexamfetamine (%) | 0 | 955 (97.3) | 822 (100.0) | 203 (97.1) | 505 (99.0) | 421 (98.6) | 1416 (99.1) | 676 (97.5) | 222 (100.0) | <0.001 |
| 1 | 27 (2.7) | 0 (0.0) | 6 (2.9) | 5 (1.0) | 6 (1.4) | 13 (0.9) | 17 (2.5) | 0 (0.0) | ||
| Lithium (%) | 0 | 950 (96.7) | 812 (98.8) | 183 (87.6) | 487 (95.5) | 420 (98.4) | 1370 (95.9) | 668 (96.4) | 214 (96.4) | <0.001 |
| 1 | 32 (3.3) | 10 (1.2) | 26 (12.4) | 23 (4.5) | 7 (1.6) | 59 (4.1) | 25 (3.6) | 8 (3.6) | ||
| Lorazepam (%) | 0 | 841 (85.6) | 359 (43.7) | 173 (82.8) | 388 (76.1) | 375 (87.8) | 1140 (79.8) | 595 (85.9) | 202 (91.0) | <0.001 |
| 1 | 141 (14.4) | 463 (56.3) | 36 (17.2) | 122 (23.9) | 52 (12.2) | 289 (20.2) | 98 (14.1) | 20 (9.0) | ||
| Lurasidone (%) | 0 | 982 (100.0) | 822 (100.0) | 0 (0.0) | 510 (100.0) | 427 (100.0) | 1429 (100.0) | 693 (100.0) | 222 (100.0) | <0.001 |
| 1 | 0 (0.0) | 0 (0.0) | 209 (100.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | ||
| Magnesium Carbonate (%) | 0 | 981 (99.9) | 822 (100.0) | 209 (100.0) | 510 (100.0) | 427 (100.0) | 1429 (100.0) | 693 (100.0) | 222 (100.0) | 0.734 |
| 1 | 1 (0.1) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | ||
| Meclizine (%) | 0 | 970 (98.8) | 807 (98.2) | 208 (99.5) | 496 (97.3) | 420 (98.4) | 1407 (98.5) | 681 (98.3) | 221 (99.5) | 0.244 |
| 1 | 12 (1.2) | 15 (1.8) | 1 (0.5) | 14 (2.7) | 7 (1.6) | 22 (1.5) | 12 (1.7) | 1 (0.5) | ||
| Melatonin (%) | 0 | 952 (96.9) | 735 (89.4) | 201 (96.2) | 463 (90.8) | 413 (96.7) | 1346 (94.2) | 659 (95.1) | 209 (94.1) | <0.001 |
| 1 | 30 (3.1) | 87 (10.6) | 8 (3.8) | 47 (9.2) | 14 (3.3) | 83 (5.8) | 34 (4.9) | 13 (5.9) | ||
| Memantine (%) | 0 | 976 (99.4) | 822 (100.0) | 209 (100.0) | 509 (99.8) | 427 (100.0) | 1423 (99.6) | 690 (99.6) | 221 (99.5) | 0.303 |
| 1 | 6 (0.6) | 0 (0.0) | 0 (0.0) | 1 (0.2) | 0 (0.0) | 6 (0.4) | 3 (0.4) | 1 (0.5) | ||
| Meperidine (%) | 0 | 974 (99.2) | 772 (93.9) | 208 (99.5) | 499 (97.8) | 416 (97.4) | 1415 (99.0) | 684 (98.7) | 221 (99.5) | <0.001 |
| 1 | 8 (0.8) | 50 (6.1) | 1 (0.5) | 11 (2.2) | 11 (2.6) | 14 (1.0) | 9 (1.3) | 1 (0.5) | ||
| Methadone (%) | 0 | 971 (98.9) | 788 (95.9) | 206 (98.6) | 501 (98.2) | 426 (99.8) | 1402 (98.1) | 681 (98.3) | 219 (98.6) | <0.001 |
| 1 | 11 (1.1) | 34 (4.1) | 3 (1.4) | 9 (1.8) | 1 (0.2) | 27 (1.9) | 12 (1.7) | 3 (1.4) | ||
| Methocarbamol (%) | 0 | 962 (98.0) | 801 (97.4) | 202 (96.7) | 498 (97.6) | 415 (97.2) | 1381 (96.6) | 685 (98.8) | 216 (97.3) | 0.136 |
| 1 | 20 (2.0) | 21 (2.6) | 7 (3.3) | 12 (2.4) | 12 (2.8) | 48 (3.4) | 8 (1.2) | 6 (2.7) | ||
| Methylergonovine (%) | 0 | 982 (100.0) | 821 (99.9) | 209 (100.0) | 504 (98.8) | 427 (100.0) | 1428 (99.9) | 693 (100.0) | 222 (100.0) | <0.001 |
| 1 | 0 (0.0) | 1 (0.1) | 0 (0.0) | 6 (1.2) | 0 (0.0) | 1 (0.1) | 0 (0.0) | 0 (0.0) | ||
| Methylnaltrexone (%) | 0 | 982 (100.0) | 819 (99.6) | 209 (100.0) | 510 (100.0) | 427 (100.0) | 1429 (100.0) | 692 (99.9) | 222 (100.0) | 0.088 |
| 1 | 0 (0.0) | 3 (0.4) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (0.1) | 0 (0.0) | ||
| Methylphenidate (%) | 0 | 944 (96.1) | 812 (98.8) | 206 (98.6) | 495 (97.1) | 424 (99.3) | 1399 (97.9) | 661 (95.4) | 215 (96.8) | <0.001 |
| 1 | 38 (3.9) | 10 (1.2) | 3 (1.4) | 15 (2.9) | 3 (0.7) | 30 (2.1) | 32 (4.6) | 7 (3.2) | ||
| Metoclopramide (%) | 0 | 953 (97.0) | 727 (88.4) | 205 (98.1) | 483 (94.7) | 408 (95.6) | 1352 (94.6) | 664 (95.8) | 215 (96.8) | <0.001 |
| 1 | 29 (3.0) | 95 (11.6) | 4 (1.9) | 27 (5.3) | 19 (4.4) | 77 (5.4) | 29 (4.2) | 7 (3.2) | ||
| Midazolam (%) | 0 | 914 (93.1) | 469 (57.1) | 197 (94.3) | 443 (86.9) | 86 (20.1) | 1272 (89.0) | 636 (91.8) | 206 (92.8) | <0.001 |
| 1 | 68 (6.9) | 353 (42.9) | 12 (5.7) | 67 (13.1) | 341 (79.9) | 157 (11.0) | 57 (8.2) | 16 (7.2) | ||
| Milnacipran (%) | 0 | 975 (99.3) | 822 (100.0) | 207 (99.0) | 508 (99.6) | 426 (99.8) | 1426 (99.8) | 689 (99.4) | 221 (99.5) | 0.19 |
| 1 | 7 (0.7) | 0 (0.0) | 2 (1.0) | 2 (0.4) | 1 (0.2) | 3 (0.2) | 4 (0.6) | 1 (0.5) | ||
| Mirtazapine (%) | 0 | 914 (93.1) | 760 (92.5) | 198 (94.7) | 454 (89.0) | 415 (97.2) | 1308 (91.5) | 628 (90.6) | 209 (94.1) | <0.001 |
| 1 | 68 (6.9) | 62 (7.5) | 11 (5.3) | 56 (11.0) | 12 (2.8) | 121 (8.5) | 65 (9.4) | 13 (5.9) | ||
| Modafinil (%) | 0 | 978 (99.6) | 819 (99.6) | 208 (99.5) | 509 (99.8) | 425 (99.5) | 1423 (99.6) | 690 (99.6) | 222 (100.0) | 0.979 |
| 1 | 4 (0.4) | 3 (0.4) | 1 (0.5) | 1 (0.2) | 2 (0.5) | 6 (0.4) | 3 (0.4) | 0 (0.0) | ||
| Morphine (%) | 0 | 926 (94.3) | 653 (79.4) | 197 (94.3) | 457 (89.6) | 270 (63.2) | 1294 (90.6) | 649 (93.7) | 213 (95.9) | <0.001 |
| 1 | 56 (5.7) | 169 (20.6) | 12 (5.7) | 53 (10.4) | 157 (36.8) | 135 (9.4) | 44 (6.3) | 9 (4.1) | ||
| Nalbuphine (%) | 0 | 973 (99.1) | 782 (95.1) | 206 (98.6) | 507 (99.4) | 379 (88.8) | 1410 (98.7) | 685 (98.8) | 221 (99.5) | <0.001 |
| 1 | 9 (0.9) | 40 (4.9) | 3 (1.4) | 3 (0.6) | 48 (11.2) | 19 (1.3) | 8 (1.2) | 1 (0.5) | ||
| Naloxone (%) | 0 | 935 (95.2) | 708 (86.1) | 200 (95.7) | 473 (92.7) | 386 (90.4) | 1327 (92.9) | 654 (94.4) | 207 (93.2) | <0.001 |
| 1 | 47 (4.8) | 114 (13.9) | 9 (4.3) | 37 (7.3) | 41 (9.6) | 102 (7.1) | 39 (5.6) | 15 (6.8) | ||
| Naltrexone (%) | 0 | 973 (99.1) | 814 (99.0) | 206 (98.6) | 506 (99.2) | 425 (99.5) | 1400 (98.0) | 687 (99.1) | 217 (97.7) | 0.048 |
| 1 | 9 (0.9) | 8 (1.0) | 3 (1.4) | 4 (0.8) | 2 (0.5) | 29 (2.0) | 6 (0.9) | 5 (2.3) | ||
| Naproxen (%) | 0 | 929 (94.6) | 764 (92.9) | 202 (96.7) | 486 (95.3) | 396 (92.7) | 1342 (93.9) | 653 (94.2) | 212 (95.5) | 0.287 |
| 1 | 53 (5.4) | 58 (7.1) | 7 (3.3) | 24 (4.7) | 31 (7.3) | 87 (6.1) | 40 (5.8) | 10 (4.5) | ||
| Naratriptan (%) | 0 | 981 (99.9) | 822 (100.0) | 209 (100.0) | 508 (99.6) | 424 (99.3) | 1429 (100.0) | 692 (99.9) | 222 (100.0) | 0.019 |
| 1 | 1 (0.1) | 0 (0.0) | 0 (0.0) | 2 (0.4) | 3 (0.7) | 0 (0.0) | 1 (0.1) | 0 (0.0) | ||
| Nefazodone (%) | 0 | 982 (100.0) | 822 (100.0) | 208 (99.5) | 510 (100.0) | 426 (99.8) | 1429 (100.0) | 693 (100.0) | 222 (100.0) | 0.018 |
| 1 | 0 (0.0) | 0 (0.0) | 1 (0.5) | 0 (0.0) | 1 (0.2) | 0 (0.0) | 0 (0.0) | 0 (0.0) | ||
| Nortriptyline (%) | 0 | 962 (98.0) | 812 (98.8) | 208 (99.5) | 495 (97.1) | 419 (98.1) | 1406 (98.4) | 679 (98.0) | 220 (99.1) | 0.226 |
| 1 | 20 (2.0) | 10 (1.2) | 1 (0.5) | 15 (2.9) | 8 (1.9) | 23 (1.6) | 14 (2.0) | 2 (0.9) | ||
| Olanzapine (%) | 0 | 982 (100.0) | 821 (99.9) | 209 (100.0) | 0 (0.0) | 426 (99.8) | 1429 (100.0) | 693 (100.0) | 222 (100.0) | <0.001 |
| 1 | 0 (0.0) | 1 (0.1) | 0 (0.0) | 510 (100.0) | 1 (0.2) | 0 (0.0) | 0 (0.0) | 0 (0.0) | ||
| Omeprazole (%) | 0 | 837 (85.2) | 705 (85.8) | 177 (84.7) | 442 (86.7) | 349 (81.7) | 1222 (85.5) | 596 (86.0) | 198 (89.2) | 0.312 |
| 1 | 145 (14.8) | 117 (14.2) | 32 (15.3) | 68 (13.3) | 78 (18.3) | 207 (14.5) | 97 (14.0) | 24 (10.8) | ||
| Opium (%) | 0 | 947 (96.4) | 776 (94.4) | 203 (97.1) | 480 (94.1) | 409 (95.8) | 1349 (94.4) | 669 (96.5) | 209 (94.1) | 0.07 |
| 1 | 35 (3.6) | 46 (5.6) | 6 (2.9) | 30 (5.9) | 18 (4.2) | 80 (5.6) | 24 (3.5) | 13 (5.9) | ||
| Orphenadrine (%) | 0 | 978 (99.6) | 821 (99.9) | 209 (100.0) | 504 (98.8) | 426 (99.8) | 1418 (99.2) | 691 (99.7) | 222 (100.0) | 0.064 |
| 1 | 4 (0.4) | 1 (0.1) | 0 (0.0) | 6 (1.2) | 1 (0.2) | 11 (0.8) | 2 (0.3) | 0 (0.0) | ||
| Oxazepam (%) | 0 | 981 (99.9) | 822 (100.0) | 209 (100.0) | 510 (100.0) | 427 (100.0) | 1427 (99.9) | 693 (100.0) | 222 (100.0) | 0.809 |
| 1 | 1 (0.1) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 2 (0.1) | 0 (0.0) | 0 (0.0) | ||
| Oxcarbazepine (%) | 0 | 969 (98.7) | 817 (99.4) | 205 (98.1) | 502 (98.4) | 423 (99.1) | 1405 (98.3) | 680 (98.1) | 217 (97.7) | 0.349 |
| 1 | 13 (1.3) | 5 (0.6) | 4 (1.9) | 8 (1.6) | 4 (0.9) | 24 (1.7) | 13 (1.9) | 5 (2.3) | ||
| Oxycodone (%) | 0 | 840 (85.5) | 480 (58.4) | 176 (84.2) | 411 (80.6) | 125 (29.3) | 1108 (77.5) | 583 (84.1) | 194 (87.4) | <0.001 |
| 1 | 142 (14.5) | 342 (41.6) | 33 (15.8) | 99 (19.4) | 302 (70.7) | 321 (22.5) | 110 (15.9) | 28 (12.6) | ||
| Oxymorphone (%) | 0 | 974 (99.2) | 811 (98.7) | 208 (99.5) | 502 (98.4) | 418 (97.9) | 1410 (98.7) | 683 (98.6) | 218 (98.2) | 0.562 |
| 1 | 8 (0.8) | 11 (1.3) | 1 (0.5) | 8 (1.6) | 9 (2.1) | 19 (1.3) | 10 (1.4) | 4 (1.8) | ||
| Pamabrom (%) | 0 | 982 (100.0) | 822 (100.0) | 208 (99.5) | 510 (100.0) | 427 (100.0) | 1429 (100.0) | 693 (100.0) | 222 (100.0) | 0.001 |
| 1 | 0 (0.0) | 0 (0.0) | 1 (0.5) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | ||
| Paroxetine (%) | 0 | 946 (96.3) | 796 (96.8) | 207 (99.0) | 495 (97.1) | 417 (97.7) | 1355 (94.8) | 660 (95.2) | 215 (96.8) | 0.01 |
| 1 | 36 (3.7) | 26 (3.2) | 2 (1.0) | 15 (2.9) | 10 (2.3) | 74 (5.2) | 33 (4.8) | 7 (3.2) | ||
| Pentazocine (%) | 0 | 982 (100.0) | 822 (100.0) | 209 (100.0) | 509 (99.8) | 427 (100.0) | 1429 (100.0) | 693 (100.0) | 222 (100.0) | 0.226 |
| 1 | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (0.2) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | ||
| Pentobarbital (%) | 0 | 982 (100.0) | 821 (99.9) | 209 (100.0) | 510 (100.0) | 427 (100.0) | 1429 (100.0) | 693 (100.0) | 222 (100.0) | 0.606 |
| 1 | 0 (0.0) | 1 (0.1) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | ||
| Perphenazine (%) | 0 | 982 (100.0) | 822 (100.0) | 209 (100.0) | 510 (100.0) | 0 (0.0) | 1429 (100.0) | 693 (100.0) | 222 (100.0) | <0.001 |
| 1 | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 427 (100.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | ||
| Phenazopyridine (%) | 0 | 968 (98.6) | 801 (97.4) | 205 (98.1) | 506 (99.2) | 407 (95.3) | 1413 (98.9) | 690 (99.6) | 221 (99.5) | <0.001 |
| 1 | 14 (1.4) | 21 (2.6) | 4 (1.9) | 4 (0.8) | 20 (4.7) | 16 (1.1) | 3 (0.4) | 1 (0.5) | ||
| Phenelzine (%) | 0 | 982 (100.0) | 822 (100.0) | 209 (100.0) | 510 (100.0) | 427 (100.0) | 1428 (99.9) | 693 (100.0) | 222 (100.0) | 0.911 |
| 1 | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (0.1) | 0 (0.0) | 0 (0.0) | ||
| Pheniramine (%) | 0 | 980 (99.8) | 821 (99.9) | 209 (100.0) | 510 (100.0) | 427 (100.0) | 1427 (99.9) | 691 (99.7) | 222 (100.0) | 0.837 |
| 1 | 2 (0.2) | 1 (0.1) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 2 (0.1) | 2 (0.3) | 0 (0.0) | ||
| Phenobarbital (%) | 0 | 978 (99.6) | 806 (98.1) | 206 (98.6) | 499 (97.8) | 427 (100.0) | 1408 (98.5) | 686 (99.0) | 219 (98.6) | 0.008 |
| 1 | 4 (0.4) | 16 (1.9) | 3 (1.4) | 11 (2.2) | 0 (0.0) | 21 (1.5) | 7 (1.0) | 3 (1.4) | ||
| Phentermine (%) | 0 | 968 (98.6) | 820 (99.8) | 208 (99.5) | 510 (100.0) | 424 (99.3) | 1421 (99.4) | 693 (100.0) | 222 (100.0) | 0.001 |
| 1 | 14 (1.4) | 2 (0.2) | 1 (0.5) | 0 (0.0) | 3 (0.7) | 8 (0.6) | 0 (0.0) | 0 (0.0) | ||
| Phenylephrine (%) | 0 | 953 (97.0) | 675 (82.1) | 205 (98.1) | 481 (94.3) | 316 (74.0) | 1370 (95.9) | 676 (97.5) | 221 (99.5) | <0.001 |
| 1 | 29 (3.0) | 147 (17.9) | 4 (1.9) | 29 (5.7) | 111 (26.0) | 59 (4.1) | 17 (2.5) | 1 (0.5) | ||
| Phenyltoloxamine (%) | 0 | 982 (100.0) | 822 (100.0) | 209 (100.0) | 510 (100.0) | 427 (100.0) | 1429 (100.0) | 693 (100.0) | 221 (99.5) | 0.002 |
| 1 | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (0.5) | ||
| Phenytoin (%) | 0 | 979 (99.7) | 799 (97.2) | 207 (99.0) | 505 (99.0) | 425 (99.5) | 1407 (98.5) | 691 (99.7) | 220 (99.1) | <0.001 |
| 1 | 3 (0.3) | 23 (2.8) | 2 (1.0) | 5 (1.0) | 2 (0.5) | 22 (1.5) | 2 (0.3) | 2 (0.9) | ||
| Pramipexole (%) | 0 | 980 (99.8) | 815 (99.1) | 208 (99.5) | 508 (99.6) | 422 (98.8) | 1416 (99.1) | 689 (99.4) | 218 (98.2) | 0.157 |
| 1 | 2 (0.2) | 7 (0.9) | 1 (0.5) | 2 (0.4) | 5 (1.2) | 13 (0.9) | 4 (0.6) | 4 (1.8) | ||
| Pregabalin (%) | 0 | 964 (98.2) | 799 (97.2) | 203 (97.1) | 497 (97.5) | 409 (95.8) | 1390 (97.3) | 674 (97.3) | 219 (98.6) | 0.307 |
| 1 | 18 (1.8) | 23 (2.8) | 6 (2.9) | 13 (2.5) | 18 (4.2) | 39 (2.7) | 19 (2.7) | 3 (1.4) | ||
| Primidone (%) | 0 | 982 (100.0) | 818 (99.5) | 209 (100.0) | 510 (100.0) | 427 (100.0) | 1424 (99.7) | 693 (100.0) | 222 (100.0) | 0.078 |
| 1 | 0 (0.0) | 4 (0.5) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 5 (0.3) | 0 (0.0) | 0 (0.0) | ||
| Promazine (%) | 0 | 981 (99.9) | 822 (100.0) | 209 (100.0) | 510 (100.0) | 427 (100.0) | 1429 (100.0) | 693 (100.0) | 222 (100.0) | 0.734 |
| 1 | 1 (0.1) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | ||
| Promethazine (%) | 0 | 962 (98.0) | 772 (93.9) | 203 (97.1) | 490 (96.1) | 401 (93.9) | 1389 (97.2) | 677 (97.7) | 218 (98.2) | <0.001 |
| 1 | 20 (2.0) | 50 (6.1) | 6 (2.9) | 20 (3.9) | 26 (6.1) | 40 (2.8) | 16 (2.3) | 4 (1.8) | ||
| Propoxyphene (%) | 0 | 982 (100.0) | 820 (99.8) | 209 (100.0) | 509 (99.8) | 426 (99.8) | 1427 (99.9) | 693 (100.0) | 222 (100.0) | 0.713 |
| 1 | 0 (0.0) | 2 (0.2) | 0 (0.0) | 1 (0.2) | 1 (0.2) | 2 (0.1) | 0 (0.0) | 0 (0.0) | ||
| Protriptyline (%) | 0 | 982 (100.0) | 822 (100.0) | 209 (100.0) | 510 (100.0) | 427 (100.0) | 1428 (99.9) | 693 (100.0) | 222 (100.0) | 0.911 |
| 1 | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (0.1) | 0 (0.0) | 0 (0.0) | ||
| Pseudoephedrine (%) | 0 | 967 (98.5) | 816 (99.3) | 207 (99.0) | 502 (98.4) | 421 (98.6) | 1420 (99.4) | 689 (99.4) | 221 (99.5) | 0.192 |
| 1 | 15 (1.5) | 6 (0.7) | 2 (1.0) | 8 (1.6) | 6 (1.4) | 9 (0.6) | 4 (0.6) | 1 (0.5) | ||
| Quetiapine (%) | 0 | 982 (100.0) | 822 (100.0) | 209 (100.0) | 508 (99.6) | 424 (99.3) | 0 (0.0) | 693 (100.0) | 219 (98.6) | <0.001 |
| 1 | 0 (0.0) | 0 (0.0) | 0 (0.0) | 2 (0.4) | 3 (0.7) | 1429 (100.0) | 0 (0.0) | 3 (1.4) | ||
| Quinidine (%) | 0 | 982 (100.0) | 822 (100.0) | 209 (100.0) | 510 (100.0) | 427 (100.0) | 1428 (99.9) | 693 (100.0) | 222 (100.0) | 0.911 |
| 1 | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (0.1) | 0 (0.0) | 0 (0.0) | ||
| Rasagiline (%) | 0 | 982 (100.0) | 822 (100.0) | 209 (100.0) | 510 (100.0) | 427 (100.0) | 1428 (99.9) | 693 (100.0) | 222 (100.0) | 0.911 |
| 1 | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (0.1) | 0 (0.0) | 0 (0.0) | ||
| Remifentanil (%) | 0 | 980 (99.8) | 811 (98.7) | 208 (99.5) | 508 (99.6) | 414 (97.0) | 1424 (99.7) | 691 (99.7) | 221 (99.5) | <0.001 |
| 1 | 2 (0.2) | 11 (1.3) | 1 (0.5) | 2 (0.4) | 13 (3.0) | 5 (0.3) | 2 (0.3) | 1 (0.5) | ||
| Riboflavin (%) | 0 | 979 (99.7) | 819 (99.6) | 209 (100.0) | 502 (98.4) | 425 (99.5) | 1424 (99.7) | 689 (99.4) | 222 (100.0) | 0.021 |
| 1 | 3 (0.3) | 3 (0.4) | 0 (0.0) | 8 (1.6) | 2 (0.5) | 5 (0.3) | 4 (0.6) | 0 (0.0) | ||
| Risperidone (%) | 0 | 981 (99.9) | 819 (99.6) | 209 (100.0) | 510 (100.0) | 427 (100.0) | 1427 (99.9) | 0 (0.0) | 220 (99.1) | <0.001 |
| 1 | 1 (0.1) | 3 (0.4) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 2 (0.1) | 693 (100.0) | 2 (0.9) | ||
| Rivastigmine (%) | 0 | 979 (99.7) | 821 (99.9) | 208 (99.5) | 509 (99.8) | 427 (100.0) | 1429 (100.0) | 691 (99.7) | 222 (100.0) | 0.412 |
| 1 | 3 (0.3) | 1 (0.1) | 1 (0.5) | 1 (0.2) | 0 (0.0) | 0 (0.0) | 2 (0.3) | 0 (0.0) | ||
| Rizatriptan (%) | 0 | 962 (98.0) | 809 (98.4) | 206 (98.6) | 495 (97.1) | 418 (97.9) | 1408 (98.5) | 682 (98.4) | 218 (98.2) | 0.576 |
| 1 | 20 (2.0) | 13 (1.6) | 3 (1.4) | 15 (2.9) | 9 (2.1) | 21 (1.5) | 11 (1.6) | 4 (1.8) | ||
| Ropinirole (%) | 0 | 969 (98.7) | 816 (99.3) | 204 (97.6) | 503 (98.6) | 423 (99.1) | 1408 (98.5) | 684 (98.7) | 218 (98.2) | 0.632 |
| 1 | 13 (1.3) | 6 (0.7) | 5 (2.4) | 7 (1.4) | 4 (0.9) | 21 (1.5) | 9 (1.3) | 4 (1.8) | ||
| Ropivacaine (%) | 0 | 973 (99.1) | 781 (95.0) | 208 (99.5) | 507 (99.4) | 359 (84.1) | 1415 (99.0) | 687 (99.1) | 221 (99.5) | <0.001 |
| 1 | 9 (0.9) | 41 (5.0) | 1 (0.5) | 3 (0.6) | 68 (15.9) | 14 (1.0) | 6 (0.9) | 1 (0.5) | ||
| Rufinamide (%) | 0 | 982 (100.0) | 822 (100.0) | 209 (100.0) | 510 (100.0) | 427 (100.0) | 1429 (100.0) | 693 (100.0) | 221 (99.5) | 0.002 |
| 1 | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (0.5) | ||
| Salicylic Acid (%) | 0 | 981 (99.9) | 821 (99.9) | 209 (100.0) | 510 (100.0) | 427 (100.0) | 1429 (100.0) | 693 (100.0) | 222 (100.0) | 0.789 |
| 1 | 1 (0.1) | 1 (0.1) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | ||
| Scopolamine (%) | 0 | 977 (99.5) | 750 (91.2) | 209 (100.0) | 504 (98.8) | 341 (79.9) | 1424 (99.7) | 685 (98.8) | 221 (99.5) | <0.001 |
| 1 | 5 (0.5) | 72 (8.8) | 0 (0.0) | 6 (1.2) | 86 (20.1) | 5 (0.3) | 8 (1.2) | 1 (0.5) | ||
| Selegiline (%) | 0 | 982 (100.0) | 821 (99.9) | 209 (100.0) | 510 (100.0) | 427 (100.0) | 1429 (100.0) | 693 (100.0) | 222 (100.0) | 0.606 |
| 1 | 0 (0.0) | 1 (0.1) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | ||
| Sertraline (%) | 0 | 803 (81.8) | 712 (86.6) | 181 (86.6) | 444 (87.1) | 374 (87.6) | 1209 (84.6) | 568 (82.0) | 189 (85.1) | 0.011 |
| 1 | 179 (18.2) | 110 (13.4) | 28 (13.4) | 66 (12.9) | 53 (12.4) | 220 (15.4) | 125 (18.0) | 33 (14.9) | ||
| Sodium Bicarbonate (%) | 0 | 981 (99.9) | 819 (99.6) | 209 (100.0) | 509 (99.8) | 426 (99.8) | 1428 (99.9) | 691 (99.7) | 222 (100.0) | 0.735 |
| 1 | 1 (0.1) | 3 (0.4) | 0 (0.0) | 1 (0.2) | 1 (0.2) | 1 (0.1) | 2 (0.3) | 0 (0.0) | ||
| Sufentanil (%) | 0 | 982 (100.0) | 821 (99.9) | 209 (100.0) | 510 (100.0) | 427 (100.0) | 1429 (100.0) | 693 (100.0) | 222 (100.0) | 0.606 |
| 1 | 0 (0.0) | 1 (0.1) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | ||
| Sumatriptan (%) | 0 | 934 (95.1) | 790 (96.1) | 192 (91.9) | 468 (91.8) | 402 (94.1) | 1371 (95.9) | 675 (97.4) | 210 (94.6) | <0.001 |
| 1 | 48 (4.9) | 32 (3.9) | 17 (8.1) | 42 (8.2) | 25 (5.9) | 58 (4.1) | 18 (2.6) | 12 (5.4) | ||
| Suvorexant (%) | 0 | 982 (100.0) | 822 (100.0) | 209 (100.0) | 510 (100.0) | 427 (100.0) | 1425 (99.7) | 693 (100.0) | 222 (100.0) | 0.146 |
| 1 | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 4 (0.3) | 0 (0.0) | 0 (0.0) | ||
| Tacrine (%) | 0 | 981 (99.9) | 822 (100.0) | 209 (100.0) | 510 (100.0) | 427 (100.0) | 1429 (100.0) | 693 (100.0) | 222 (100.0) | 0.734 |
| 1 | 1 (0.1) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | ||
| Tapentadol (%) | 0 | 981 (99.9) | 821 (99.9) | 209 (100.0) | 509 (99.8) | 427 (100.0) | 1429 (100.0) | 693 (100.0) | 222 (100.0) | 0.732 |
| 1 | 1 (0.1) | 1 (0.1) | 0 (0.0) | 1 (0.2) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | ||
| Tasimelteon (%) | 0 | 982 (100.0) | 821 (99.9) | 209 (100.0) | 510 (100.0) | 427 (100.0) | 1429 (100.0) | 693 (100.0) | 222 (100.0) | 0.606 |
| 1 | 0 (0.0) | 1 (0.1) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | ||
| Temazepam (%) | 0 | 963 (98.1) | 797 (97.0) | 203 (97.1) | 495 (97.1) | 423 (99.1) | 1383 (96.8) | 668 (96.4) | 216 (97.3) | 0.135 |
| 1 | 19 (1.9) | 25 (3.0) | 6 (2.9) | 15 (2.9) | 4 (0.9) | 46 (3.2) | 25 (3.6) | 6 (2.7) | ||
| Thiamine (%) | 0 | 961 (97.9) | 715 (87.0) | 201 (96.2) | 470 (92.2) | 418 (97.9) | 1343 (94.0) | 666 (96.1) | 212 (95.5) | <0.001 |
| 1 | 21 (2.1) | 107 (13.0) | 8 (3.8) | 40 (7.8) | 9 (2.1) | 86 (6.0) | 27 (3.9) | 10 (4.5) | ||
| Tiagabine (%) | 0 | 981 (99.9) | 822 (100.0) | 209 (100.0) | 510 (100.0) | 427 (100.0) | 1429 (100.0) | 692 (99.9) | 222 (100.0) | 0.719 |
| 1 | 1 (0.1) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (0.1) | 0 (0.0) | ||
| Topiramate (%) | 0 | 891 (90.7) | 785 (95.5) | 177 (84.7) | 460 (90.2) | 395 (92.5) | 1308 (91.5) | 645 (93.1) | 189 (85.1) | <0.001 |
| 1 | 91 (9.3) | 37 (4.5) | 32 (15.3) | 50 (9.8) | 32 (7.5) | 121 (8.5) | 48 (6.9) | 33 (14.9) | ||
| Tramadol (%) | 0 | 910 (92.7) | 732 (89.1) | 196 (93.8) | 471 (92.4) | 368 (86.2) | 1304 (91.3) | 649 (93.7) | 204 (91.9) | <0.001 |
| 1 | 72 (7.3) | 90 (10.9) | 13 (6.2) | 39 (7.6) | 59 (13.8) | 125 (8.7) | 44 (6.3) | 18 (8.1) | ||
| Tranylcypromine (%) | 0 | 981 (99.9) | 822 (100.0) | 209 (100.0) | 510 (100.0) | 427 (100.0) | 1429 (100.0) | 693 (100.0) | 222 (100.0) | 0.734 |
| 1 | 1 (0.1) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | ||
| Trazodone (%) | 0 | 781 (79.5) | 691 (84.1) | 173 (82.8) | 418 (82.0) | 386 (90.4) | 1164 (81.5) | 547 (78.9) | 189 (85.1) | <0.001 |
| 1 | 201 (20.5) | 131 (15.9) | 36 (17.2) | 92 (18.0) | 41 (9.6) | 265 (18.5) | 146 (21.1) | 33 (14.9) | ||
| Triazolam (%) | 0 | 980 (99.8) | 821 (99.9) | 209 (100.0) | 509 (99.8) | 427 (100.0) | 1427 (99.9) | 693 (100.0) | 222 (100.0) | 0.897 |
| 1 | 2 (0.2) | 1 (0.1) | 0 (0.0) | 1 (0.2) | 0 (0.0) | 2 (0.1) | 0 (0.0) | 0 (0.0) | ||
| Trifluoperazine (%) | 0 | 982 (100.0) | 822 (100.0) | 209 (100.0) | 510 (100.0) | 427 (100.0) | 1429 (100.0) | 692 (99.9) | 222 (100.0) | 0.467 |
| 1 | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (0.1) | 0 (0.0) | ||
| Valbenazine (%) | 0 | 981 (99.9) | 822 (100.0) | 209 (100.0) | 510 (100.0) | 427 (100.0) | 1429 (100.0) | 693 (100.0) | 222 (100.0) | 0.734 |
| 1 | 1 (0.1) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | ||
| Valproate (%) | 0 | 977 (99.5) | 812 (98.8) | 209 (100.0) | 500 (98.0) | 426 (99.8) | 1420 (99.4) | 690 (99.6) | 221 (99.5) | 0.012 |
| 1 | 5 (0.5) | 10 (1.2) | 0 (0.0) | 10 (2.0) | 1 (0.2) | 9 (0.6) | 3 (0.4) | 1 (0.5) | ||
| Venlafaxine (%) | 0 | 842 (85.7) | 764 (92.9) | 188 (90.0) | 472 (92.5) | 395 (92.5) | 1269 (88.8) | 622 (89.8) | 195 (87.8) | <0.001 |
| 1 | 140 (14.3) | 58 (7.1) | 21 (10.0) | 38 (7.5) | 32 (7.5) | 160 (11.2) | 71 (10.2) | 27 (12.2) | ||
| Vilazodone (%) | 0 | 974 (99.2) | 821 (99.9) | 205 (98.1) | 509 (99.8) | 420 (98.4) | 1423 (99.6) | 690 (99.6) | 221 (99.5) | 0.004 |
| 1 | 8 (0.8) | 1 (0.1) | 4 (1.9) | 1 (0.2) | 7 (1.6) | 6 (0.4) | 3 (0.4) | 1 (0.5) | ||
| Vitamin B6 (%) | 0 | 978 (99.6) | 818 (99.5) | 208 (99.5) | 508 (99.6) | 427 (100.0) | 1427 (99.9) | 691 (99.7) | 221 (99.5) | 0.739 |
| 1 | 4 (0.4) | 4 (0.5) | 1 (0.5) | 2 (0.4) | 0 (0.0) | 2 (0.1) | 2 (0.3) | 1 (0.5) | ||
| Vortioxetine (%) | 0 | 970 (98.8) | 821 (99.9) | 206 (98.6) | 508 (99.6) | 425 (99.5) | 1425 (99.7) | 691 (99.7) | 220 (99.1) | 0.012 |
| 1 | 12 (1.2) | 1 (0.1) | 3 (1.4) | 2 (0.4) | 2 (0.5) | 4 (0.3) | 2 (0.3) | 2 (0.9) | ||
| Zaleplon (%) | 0 | 981 (99.9) | 820 (99.8) | 208 (99.5) | 508 (99.6) | 427 (100.0) | 1428 (99.9) | 691 (99.7) | 220 (99.1) | 0.205 |
| 1 | 1 (0.1) | 2 (0.2) | 1 (0.5) | 2 (0.4) | 0 (0.0) | 1 (0.1) | 2 (0.3) | 2 (0.9) | ||
| Ziprasidone (%) | 0 | 982 (100.0) | 821 (99.9) | 208 (99.5) | 509 (99.8) | 427 (100.0) | 1429 (100.0) | 693 (100.0) | 0 (0.0) | <0.001 |
| 1 | 0 (0.0) | 1 (0.1) | 1 (0.5) | 1 (0.2) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 222 (100.0) | ||
| Zolmitriptan (%) | 0 | 982 (100.0) | 822 (100.0) | 208 (99.5) | 508 (99.6) | 427 (100.0) | 1428 (99.9) | 692 (99.9) | 222 (100.0) | 0.155 |
| 1 | 0 (0.0) | 0 (0.0) | 1 (0.5) | 2 (0.4) | 0 (0.0) | 1 (0.1) | 1 (0.1) | 0 (0.0) | ||
| Zolpidem (%) | 0 | 908 (92.5) | 734 (89.3) | 195 (93.3) | 467 (91.6) | 401 (93.9) | 1303 (91.2) | 653 (94.2) | 206 (92.8) | 0.016 |
| 1 | 74 (7.5) | 88 (10.7) | 14 (6.7) | 43 (8.4) | 26 (6.1) | 126 (8.8) | 40 (5.8) | 16 (7.2) | ||
| Zonisamide (%) | 0 | 978 (99.6) | 818 (99.5) | 207 (99.0) | 506 (99.2) | 427 (100.0) | 1425 (99.7) | 692 (99.9) | 221 (99.5) | 0.388 |
| 1 | 4 (0.4) | 4 (0.5) | 2 (1.0) | 4 (0.8) | 0 (0.0) | 4 (0.3) | 1 (0.1) | 1 (0.5) | ||
| Doxazosin (%) | 0 | 980 (99.8) | 819 (99.6) | 209 (100.0) | 509 (99.8) | 425 (99.5) | 1424 (99.7) | 693 (100.0) | 222 (100.0) | 0.676 |
| 1 | 2 (0.2) | 3 (0.4) | 0 (0.0) | 1 (0.2) | 2 (0.5) | 5 (0.3) | 0 (0.0) | 0 (0.0) | ||
| Prazosin (%) | 0 | 882 (89.8) | 800 (97.3) | 184 (88.0) | 463 (90.8) | 408 (95.6) | 1276 (89.3) | 642 (92.6) | 205 (92.3) | <0.001 |
| 1 | 100 (10.2) | 22 (2.7) | 25 (12.0) | 47 (9.2) | 19 (4.4) | 153 (10.7) | 51 (7.4) | 17 (7.7) | ||
| Terazosin (%) | 0 | 980 (99.8) | 815 (99.1) | 208 (99.5) | 509 (99.8) | 426 (99.8) | 1428 (99.9) | 690 (99.6) | 222 (100.0) | 0.081 |
| 1 | 2 (0.2) | 7 (0.9) | 1 (0.5) | 1 (0.2) | 1 (0.2) | 1 (0.1) | 3 (0.4) | 0 (0.0) | ||