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Knockdown of GAS5 suppressed RBE cell proliferation and invasion. (A) GAS5 is upregulated in CCA cell lines compared with that in the HIBEC cell, *p<0.05, **p<0.01. (B) qRT-PCR was used to detect the expression of GAS5 in RBE cells transfected with si-GAS5, **p<0.01. (C) CCK-8 assay was applied to observe the effect of GAS5 on RBE cell proliferation, **p<0.01. (D) Transwell assay was used to explore the role of GAS5 on RBE cell invasion. **p < 0.01 compared to the control group.
