Table A1.
Model metrics in cross-validation (mean with confidence intervals) and on the test set using CpG probes derived from RNA. ACC: accuracy; MCC: Matthews Correlation, prec: Precision, recal: Recall Coefficient; CI: 95% studentized bootstrap confidence interval; RF: Random Forest.
| Model | Regions | ACC (CI) | ACC Test | MCC (CI) | MCC Test |
|---|---|---|---|---|---|
| RF | IImmuneAngioICIsMesECM-ISLAND | 0.724 (0.688–0.769) | 0.747 | 0.460 (0.389–0.549) | 0.522 |
| RF | ImmuneAngioICIsMesECM-OPENSEA | 0.725 (0.689–0.762) | 0.691 | 0.456 (0.386–0.533) | 0.469 |
| RF | ImmuneAngioICIsMesECM-SHORE | 0.749 (0.705–0.790) | 0.774 | 0.501 (0.417–0.583) | 0.553 |
| RF | ImmuneAngioICIsMesECM-SHELF | 0.758 (0.722–0.789) | 0.747 | 0.529 (0.459–0.593) | 0.510 |
| RF | ImmuneAngioICIs-ISLAND | 0.756 (0.716–0.792) | 0.758 | 0.514 (0.439–0.587) | 0.518 |
| RF | ImmuneAngioICIs-SHORE | 0.753 (0.710–0.798) | 0.734 | 0.509 (0.422–0.598) | 0.536 |
| RF | ImmuneAngioICIs- OPENSEA | 0.729 (0.757–0.700) | 0.738 | 0.463 (0.406–0.520) | 0.490 |
| RF | ImmuneAngioICIs-SHELF | 0.725 (0.685–0.763) | 0.720 | 0.457 (0.373–0.537) | 0.543 |