Table A3.

Top features detected by permutation analysis from Random Survival Forest using PFS selected by 338 CpG probes.

Feature	Weight	std	Gene	Direction
cg02458945	0.00167149	0.0004095	MMP2	Positive
cg03478249	0.00245778	0.00088256	EPSTI1	Positive
cg04131610	0.00323843	0.00146985	CCR5, RP11-24F11.2	Positive
cg04217515	0.00200311	0.00073152	ITGB2	Positive
cg04244970	0.00166519	0.00067762	SLAMF7	Positive
cg05091653	0.00216262	0.00032063	SP100	Positive
cg05887821	0.00216972	0.00032553	INPP5A	Positive
cg07623567	0.00210498	0.00037064	HLA-DMB, XXbac-BPG181M17.5	Positive
cg08612539	0.00185325	0.00028535	CTA-833B7.2, NCF4	Positive
cg09076123	0.00165326	0.0007419	NCF2, SMG7	Positive
cg10307548	0.00294971	0.00098171	SOD3	Positive
cg10330169	0.00418932	0.00097532	DIS3L2	Positive
cg11197101	0.00227763	0.00036055	KIAA1522	Positive
cg13865810	0.00176505	0.00045972	COL15A1, RP11-92C4.6	Positive
cg16436782	0.00390891	0.00123599	RP11-212E4.1, COL4A1	Positive
cg17331738	0.00264999	0.00031466	NES	Positive
cg19722814	0.00184012	0.00034522	SERPINE1	Positive
cg21475610	0.00337569	0.00100237	CCNG2	Positive
cg24192663	0.00203206	0.00052522	HSPA6, RP11-25K21.6, FCGR2A	Positive
cg24815934	0.00283711	0.00098436	ITGB2	Positive
cg00450164	−2.33 $\times {10}^{-5}$	0.00011302	TRAF3IP3	Negative
cg00532319	−5.25 $\times {10}^{-5}$	9.97 $\times {10}^{-5}$	RPN1	Negative
cg00539174	−1.10 $\times {10}^{-5}$	0.0001254	CTSZ	Negative
cg01623438	−0.0001147	0.00016634	CTSZ	Negative
cg23008352	−6.65 $\times {10}^{-5}$	0.00011621	COL4A1	Negative