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. 2021 Mar 9;10(3):321. doi: 10.3390/pathogens10030321

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Toxocara spp.-mediated cytokine secretion (A) and MHC-II surface marker expression (B) of wild-type (WT) and MGL-1^−/− bone marrow-derived dendritic cells (BMDCs). Graphs are presented as mean + SD of two experiments in duplicates. A p-value ≤ 0.05 was considered statistically significant. TSOM: Toxocara somatic antigen, TES: Toxocara excretory-secretory antigen, LPS: positive control. Note that in this assay co-stimulation of Toxocara antigens with LPS was performed due to functional reasons (cf. Section 4.7).