Table 3.
Studies reporting on long-term follow-up after FMT.
| Author | Study Design | Patients Treated with FMT | Deaths | Patients Included for Follow-Up | Mean Age | Mean Follow-Up | Primary Cure * | Patients with New Episodes of CDI | Patients Receiving Antibiotics Post-FMT ** | Safety: SAEs Possibly Attributable to FMT |
|---|---|---|---|---|---|---|---|---|---|---|
| Van Beurden et al. [6]. | Retrospective cohort | 43 | 8 (19%) | 39 | 73 | 21 months | 82% | 7 (18%) | NA | Not reported |
| Perler et al. [20]. | Retrospective cohort | 528 | 52 (10%) | 207 | 58 | 34 months | 89% | 51 (25%) | 100 (48%) | Not reported |
| Lee et al. [18]. | Retrospective cohort | 94 | 37 (39%) | 23 | NA | 6 years | NA | 0 | 12 (52%) | Not reported |
| Girotra et al. [16]. | Prospective observational cohort | 29 | 0 | 29 | 80 | 12 months | 100% | 0 | NA | Not reported |
| Mamo et al. [19]. | Retrospective cohort | 232 | 26 (11%) | 137 | 66 | 22 months | NA | 24 (18%) | 61 (45%) | Not reported |
| Greenwald et al. [15]. | Retrospective cohort | 79 | 0 | 58 | 69 | 18 months | NA | 11 (19%) | NA | Not reported |
| Jalanka et al. [17]. | Retrospective cohort | NA | 0 | 55 | 57 | 3.4 years | NA | 2 (4%) | 26 (47%) | Not reported |
* Primary cure is defined as a resolution of CDI symptoms for 48 consecutive hours post-FMT. ** At least one course of non-CDI antibiotics. Abbreviations: CDI: Clostridioides difficile infection, FMT: fecal microbiota transplantation, NA: not available, SAEs: serious adverse events.