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. 2021 Mar 9;13(3):887. doi: 10.3390/nu13030887

Table 4.

Factors that influence exertional hyponatremia. Letters in column 1 refer to the symbols embedded in Figure 2.

Symbols in Figure 2 Men Women Scenario (Ambient Temperature, °C) Final Serum Na+ (mmol/L) Body Mass Change (%) Exercise Duration (h) Rate of Fluid Intake (ml/h) Mean Initial Body Mass (kg) Source
Background data points a a 11 endurance events a See Figure 3 See Figure 3 b b b [20]
A 42 164 km cycling (34.4) 141 −0.8 9.1 649 85.9 [55]
B 31 164 km cycling (24.4–39.5) 141 −1.4 9.0 700 85.4 [66]
C 6 164 km cycling (34.4) 140 −0.1 9.0 520 67.3 [55]
D 50 100 km run (15.6–21.7) 138 −2.6 12.2 600 74.9 [71]
E 7 Treadmill walk (41.0) c 136 −0.1 4.0 c 640 77.9 [61]
F 5 44 km trail run (15–34) 131 −2.2 9.3 290 d 81.9 [72]
G 1 Ironman triathlon
(21.0) e,f
131 +0.9 13.3 733 57.5 [73]
H 1 164 km cycling (24.4–39.5) g 130 +4.3 8.9 1,500 72.0 [66]
I 1 Ironman triathlon
(21.0) e,f
130 +2.5 12.0 764 59.0 [73]
J 1 164 km cycling (24.4–39.5) g 130 +0.1 10.6 1,400 77.5 [66]
K 2 5 Ironman triathlon e 128 −0.5 12.3 b 62.5 [74]
L 1 Treadmill walk (41.0) c 122 +4.0 4.0 c 2,061 h 82.2 [61]
M 1 Ironman triathlon e 116 +5.0 14.0 1,642 b [75]

Note: values are means or medians (columns 5–9) when the number of subjects is ≥ 2. a, 3 Ironman triathlons, 6 marathon footraces (42.2 km), a 109 km cycling tour, and a 160 km footrace (2,135 athletes); b, not reported; c, 5.6 km/h, 5% grade, 30 min walking and 30 min seated rest per hour; d, runners were allowed to drink and eat only fluids and food provided by the race organizing committee, at 11 intermediate checkpoint stations, positioned every 3–5 km; they did not drink when thirsty or ad libitum; e, triathlon stages were 3.8 km swim, 180 km cycle, 42.2 km run; f, this athlete stopped during the cycling stage due to hyponatremic illness; g, identical to cyclists LC and AM in Table 4 (column 1); h, this individual purposefully overhydrated.