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. 2021 Mar 14;22(6):2949. doi: 10.3390/ijms22062949

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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An example of an RP-HPLC-MS/MS chromatogram of the WIQP peptide acting as a DPP-IV inhibitor identified in all Gouda cheese variants. Samples derived from: ChCN↓-1 (a), ChCN↓-60 (b), ChCN-0-1 (c), ChCN-0-60 (d), ChCN↑-1 (e), ChCN↑-60 (f), respectively. Abbreviations: ChCN↓-1, ChCN↓-60, ChCN-0-1, ChCN-0-60, ChCN↑-1, ChCN↑-60—water-soluble extracts derived from Gouda cheese with: reduced (↓), normative (0), and increased (↑) content of β-casein after 1 (suffix 1) and 60 (suffix 60) days of ripening, respectively.