Table 1.
Number of DPP-IV and ACE inhibitors potentially present in bovine casein sequences.
| Casein/Gen. var. | F a | Number of Peptides Present in Caseins | Total | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2- b | 3- | 4- | 5- | 6- | 7- | 8- | 9- | 10- | 11- | 12- | 13- | 14- | 19- | |||
| αS1/A | ACEi c | 72 | 6 | 4 | 2 | 5 | 1 | 2 | 1 | - | - | - | - | - | - | 93 |
| DPP-IVi d | 113 | 1 | - | - | - | - | - | - | - | - | - | - | - | - | 114 | |
| αS1/B | ACEi | 76 | 7 | 5 | 3 | 5 | 1 | 2 | 1 | - | - | - | - | - | - | 100 |
| DPP-IVi | 121 | 1 | - | - | - | - | - | - | - | - | - | - | - | - | 122 | |
| αS1/C | ACEi | 77 | 7 | 5 | 3 | 5 | 1 | 2 | 1 | - | - | - | - | - | - | 101 |
| DPP-IVi | 120 | 1 | - | - | - | - | - | - | - | - | - | - | - | - | 121 | |
| αS1/D | ACEi | 79 | 8 | 6 | 3 | 5 | 2 | 2 | 1 | - | - | 1 | - | - | - | 107 |
| DPP-IVi | 131 | 1 | - | - | - | - | - | - | - | - | - | - | - | - | 132 | |
| αS2/A | ACEi | 65 | 9 | 1 | 3 | 3 | 1 | 3 | 2 | - | 1 | - | - | - | - | 88 |
| DPP-IVi | 151 | 1 | 1 | - | 1 | - | - | - | - | - | - | - | - | - | 154 | |
| β/A1 | ACEi | 66 | 14 | 5 | 4 | 6 | 7 | 5 | 5 | 4 | 1 | 1 | 1 | 1 | - | 120 |
| DPP-IVi | 159 | 3 | 2 | - | - | 1 | - | 1 | - | - | - | - | - | - | 166 | |
| β/A2 | ACEi | 67 | 14 | 5 | 5 | 6 | 7 | 6 | 6 | 4 | 1 | 1 | 1 | 1 | 1 | 125 |
| DPP-IVi | 160 | 3 | 2 | - | - | 2 | - | 1 | - | - | - | - | - | - | 168 | |
| β/A3 | ACEi | 66 | 14 | 5 | 4 | 6 | 7 | 5 | 5 | 4 | 1 | 1 | 1 | 1 | - | 120 |
| DPP-IVi | 158 | 3 | 2 | - | - | 1 | - | 1 | - | - | - | - | - | - | 165 | |
| β/B | ACEi | 69 | 14 | 6 | 6 | 7 | 8 | 5 | 6 | 3 | 1 | 1 | 1 | 1 | 1 | 129 |
| DPP-IVi | 159 | 4 | 2 | 1 | - | 2 | - | 1 | - | - | - | - | - | - | 169 | |
| β/C | ACEi | 67 | 14 | 5 | 4 | 6 | 7 | 5 | 5 | 4 | 1 | 1 | 1 | 1 | - | 121 |
| DPP-IVi | 160 | 3 | 2 | - | - | 1 | - | 1 | - | - | - | - | - | - | 167 | |
| β/E | ACEi | 68 | 14 | 5 | 5 | 6 | 7 | 6 | 6 | 4 | 1 | 1 | 1 | 1 | 1 | 126 |
| DPP-IVi | 162 | 3 | 2 | - | - | 2 | - | 1 | - | - | - | - | - | - | 170 | |
| β/F | ACEi | 65 | 13 | 5 | 4 | 6 | 7 | 5 | 5 | 4 | 1 | 1 | 1 | 1 | - | 118 |
| DPP-IVi | 159 | 3 | 2 | - | - | 1 | - | 1 | - | - | - | - | - | - | 166 | |
| κ/A | ACEi | 53 | 10 | 4 | 5 | 5 | 1 | - | 1 | 1 | - | - | - | - | - | 80 |
| DPP-IVi | 142 | 2 | 1 | 2 | - | - | - | - | - | - | - | - | - | - | 147 | |
a biological function; b numbers from 2 to 19 refer to the number of residues in a peptide chain; c ACEi—ACE inhibitor; d DPP-IVi—dipeptidyl peptidase IV inhibitor.