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. 2021 Mar 9;11(3):190. doi: 10.3390/membranes11030190

Figure 4.

Figure 4

Effects of the mutations of the conserved tryptophan residue on the Kv2.1, Kv2.2, and Kv1.2 channel currents in HEK293 cells. (A) Representative currents for the Kv2.1 wild-type, W366A, and W366F mutant channels. (B) Representative currents for the Kv2.2 wild-type, W374A, and W374F mutant channels. (C) Representative currents for the Kv1.2 wild-type, W367A, and W367F mutant channels. (D) I-V plots of the outward currents of the Kv2.1, Kv2.2, and Kv1.2 wild-type and mutant channels (n = 7–14).