Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Mar 10;11(3):491. doi: 10.3390/diagnostics11030491

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Boxplots (A) presenting positive correlation (* p = 0.001 in Spearman-Rho) between COX-2 positive tissue amount and the individual degree of tumor grading (G1: well-differentiated for (B), G2: moderately-differentiated for (C), G3: poorly-differentiated for (D)). The boxplots indicate mild outliers, which are marked with circles. These outliers show an interquartile distance to the third quartile of values that is less than three times higher than the third quartile of values. The numbers on the circles denote the cases (case numbers 5, 37, 57) in concern. Immunohistochemistry staining of cytoplasmic COX-2 (10× and 25× magnification) showing correlation to Grading 1–3 with increase of COX-2 intensity in vulvar cancer (B–D). The medians of the percentage COX-2 expression shown in the boxplots of the individual grading categories are represented in the immunohistochemical images of (B–D) (amount 10% in (B), amount 20% in (C), and amount 40% in (D)).

Boxplots (A) presenting positive correlation (* p = 0.001 in Spearman-Rho) between COX-2 positive tissue amount and the individual degree of tumor grading (G1: well-differentiated for (B), G2: moderately-differentiated for (C), G3: poorly-differentiated for (D)). The boxplots indicate mild outliers, which are marked with circles. These outliers show an interquartile distance to the third quartile of values that is less than three times higher than the third quartile of values. The numbers on the circles denote the cases (case numbers 5, 37, 57) in concern. Immunohistochemistry staining of cytoplasmic COX-2 (10× and 25× magnification) showing correlation to Grading 1–3 with increase of COX-2 intensity in vulvar cancer (B–D). The medians of the percentage COX-2 expression shown in the boxplots of the individual grading categories are represented in the immunohistochemical images of (B–D) (amount 10% in (B), amount 20% in (C), and amount 40% in (D)).