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. 2021 Mar 23;14:1007–1017. doi: 10.2147/JIR.S302944

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© 2021 Song et al.

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CTRP9 promotes macrophage mitochondrial fission through the activation of p38/Jnk MAPK signaling. (A–C) The protein levels of JNK, ERK, P-38 induced by 1 µg/mL CTRP9 for 0–2 h. (D–F) Immunoblot analysis of Erk, p38 and Jnk after interrupted by CTRP9 and U0126, SB203580, SP600125 (10 µM 1h). (G) Immunoblot analysis of p-drp1 s616 after interrupted by 1 µg/mL CTRP9 and U0126, SB203580, SP600125. All data are expressed as mean ± SD (n=3). “ns” means no significance. ns, p >0.05; *p< 0.05; **p<0.01; ***p<0.001, ****p<0.0001; versus control. ^##p<0.01; versus CTRP9 group.