Skip to main content
. 2021 Mar 14;26(6):1613. doi: 10.3390/molecules26061613

Figure 5.

Figure 5

Crystallographic pose of the co-crystallized ligand (a), and docking pose of GEN (b) in the BF3 pocket of wild type AR (PDB ID 2ylp [68]). Crystallographic pose of the same co-crystallized ligand (c), and docking pose of GEN (d) in the AF2 pocket of wild type AR (PDB ID 2ylp [68]). The protein is shown in transparent blue cartoon, the residues lining the binding site and the ligands are shown in capped sticks and colored blue and yellow, respectively. Helices and residues lining the pocket are labelled, hydrogen bonds are displayed as black dashed lines. Water molecules are represented as red spheres.