Table 1.
Serum lipid profile and liver function enzymes in different groups of animals at the end of the experimental period.
| Parameters/Groups | NCt | DBCt | DMH | DMLL | DMLH |
|---|---|---|---|---|---|
| Total cholesterol (mmol/L) | 2.75 ± 0.64 a | 4.70 ± 0.13 c | 3.91 ± 0.35 b | 2.17 ± 0.17 a | 2.46 ± 0.46 a |
| Triacylglycerols (mmol/L) | 1.43 ± 0.29 a | 2.47 ± 0.03 b | 1.69 ± 0.03 a | 1.64 ± 0.64 a | 1.58 ± 0.58 a |
| HDL-chol. (mmol/L) | 1.15 ± 0.54 b | 0.75 ± 0.05 a | 1.10 ± 0.03 ab | 1.06 ± 0.06 ab | 1.18 ± 0.18 ab |
| LDL-chol. (mmol/L) | 1.26 ± 0.69 a | 2.89 ± 0.78 b | 1.72 ± 0.73 a | 0.76 ± 0.05 a | 0.96 ± 0.06 a |
| AST (U/min/mL) | 13.11 ± 1.07 a | 19.89 ± 0.84 d | 16.66 ± 0.66 c | 15.33 ± 0.33 b | 13.54 ± 0.46 a |
| ALT (U/min/mL) | 10.21 ± 0.51 a | 16.67 ± 0.01 d | 15.29 ± 0.61 cd | 14.66 ± 0.66 c | 12.17 ± 1.49 b |
| ALP (U/min/mL) | 14.90 ± 0.46 a | 19.28 ± 0.22 d | 15.53 ± 0.52 ab | 18.00 ± 1.00 c | 16.65 ± 0.65 b |
| Total bilirubin (mg/dL) | 0.51 ± 0.03 b | 0.65 ± 0.04 c | 0.48 ± 0.03 b | 0.39 ± 0.01 a | 0.45 ± 0.05 b |
Data of measurements from five animals are presented as mean ± standard deviation (SD). a–d Presence of the same superscripts in a column indicates no significant difference (p > 0.05), while different superscripts in a column indicate significant difference (p < 0.05). *NCt: Normal control; DBCt: Diabetic control; DMH: Diabetic + 5 mg/kg body weight free MH; DMLL: Diabetic + low dose (2.5 mg/kg body weight MH-LLV); DMLH: Diabetic + high dose (5 mg/kg body weight MH-LLV); HDL-chol.—high-density lipoprotein cholesterol; LDL-chol.—low-density lipoprotein cholesterol; AST – aspartate aminotransferase; ALT – alanine aminotransferase, ALP – alkaline phosphatase.