Conformational exchange processes in 3D and the 3D domain of 3CD on the μs-ms timescale. (a) Rex, the contribution to transverse relaxation from conformational exchange, from multiple quantum 1H-13C CPMG relaxation dispersion for 3D plotted as colored spheres (gray: no detectable exchange, blue < 2–3 s−1, purple: 3–10 s−1). (b) Multiple quantum 1H-13CHHHH CPMG relaxation dispersion curve for Ile295 in 3D. (c) Rex from multiple quantum 1H-13C CPMG relaxation dispersion for 3CD plotted as colored spheres (gray: no detectable exchange, purple: 3–10 s−1, red > 10 s−1). (d) Multiple quantum 1H-13CHHHH CPMG relaxation dispersion curve for Ile295 in the 3D domain of 3CD. 3D numbering is used here for both 3D and the 3D domain in 3CD; to find the corresponding number in 3CD, the reader would need to add 183.