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. 2021 Mar 7;10(3):314. doi: 10.3390/pathogens10030314

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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LMM6 effect on organs relative weight of male Balb/c mice in acute toxicity study. (A) Brain weight; (B) Heart weight; (C) Kidneys weight; (D) Liver weight; (E) Lungs weight and (F) spleen weight. HLTY: healthy animals; IP control: treated intraperitoneally with the vehicle; IV control: treated intravenously with the vehicle; IP LMM6: treated with 50 mg/kg of LMM6 intraperitoneally; IV LMM6: treated with 25 mg/kg of LMM6 intravenously. Organs weight were determined following 14 days exposure to high LMM6 concentration in single dose. Each data represents the mean ± standard deviation (error bars). * p < 0.05, statistically significant changes in relation to mice.