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. 2021 Mar 16;10(3):230. doi: 10.3390/biology10030230

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Change in AIS grading in human studies of MSC transplantation. The changes in a whole AIS grade have been shown for each phase of SCI when the participants were treated. Top left panel: participants with a baseline AIS grade of American Spinal Injury Association (ASIA) A and their recorded improvement. Top right panel: participants with a baseline AIS grade of ASIA B and their recorded improvement. Bottom left panel: participants with a baseline AIS grade of ASIA C and their recorded improvement. Bottom right panel: no participants with a baseline AIS grade of ASIS D improved to ASIA E (normal motor and sensory function).