Table 1.
Mice | Experimental Conditions | Baseline DA | Baseline DOPAC |
---|---|---|---|
non-Tg | aCSF | 10.3 ± 1.6 (15) | 0.8 ± 0.1 (15) |
aCSF + DMSO 1% | 7.2 ± 2.2 (4) | 1.6 ± 0.4 (4) | |
A30P*A53T*α-Syn | aCSF | 8.5 ± 1.2 (15) | 1.1 ± 0.1 (15) |
aCSF + DMSO 1% | 6.6 ± 1.7 (5) | 1.8 ± 0.5 (5) |
Extracellular DA and DOPAC levels are expressed as the fmol/20-min fraction. In the experiments involving the evaluation of the veratridine effect on extracellular DA and DOPAC levels, dimethyl-sulfoxide (DMSO) was added to the artificial cerebrospinal fluid (aCSF), respectively. Data are the mean ± SEM of the number of mice shown in parentheses.